UCSF

ZINC12501969

Substance Information

In ZINC since Heavy atoms Benign functionality
May 16th, 2008 15 Yes

CAS Number: 3/2/5746

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -4.08 1.5 -88.89 5 6 0 125 218.253 8

Vendor Notes

Note Type Comments Provided By
UniProt Database Links CEL_HUMAN; CHBF_ECOLI; CHBG_ECOLI; IFA1_CAEEL; IFA2_CAEEL; IFA3_CAEEL; IFA4_CAEEL; IFB1_CAEEL; IFB2_CAEEL; IFC1_CAEEL; IFC2_CAEEL; IFD1_CAEEL; IFD2_CAEEL; IFP1_CAEEL; LEG10_HUMAN; LEG10_MOUSE; LEG10_PONPY; PPK4_CELBM; PTEA_GEOSE; PTEB_AERHY; PTEB_GEOSE; P ChEBI
Reactome Database Links REACT_163645; REACT_163850; REACT_163962; REACT_25020; REACT_25269; REACT_25382 ChEBI

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Advanced glycosylation endproduct receptor signaling
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
RIP-mediated NFkB activation via ZBP1
Scavenging by Class A Receptors
Scavenging by Class H Receptors
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation

Analogs ( Draw Identity 99% 90% 80% 70% )