| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 22 | No |
Popular Name: 3-(4-chlorobenzoyl)-1-phenyl-imidazolidine-2,4-dione 3-(4-chlorobenzoyl)-1-phenyl-imi…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.36 | 9.7 | -15.03 | 0 | 5 | 0 | 58 | 314.728 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CATG-1-E | Cathepsin G (cluster #1 Of 2), Eukaryotic | Eukaryotes | 3000 | 0.35 | Binding ≤ 10μM |
| CTRA-1-E | Alpha-chymotrypsin (cluster #1 Of 4), Eukaryotic | Eukaryotes | 230 | 0.42 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CTRA_BOVIN | P00766 | Alpha-chymotrypsin, Bovin | 230 | 0.42 | Binding ≤ 1μM |
| CTRA_BOVIN | P00766 | Alpha-chymotrypsin, Bovin | 230 | 0.42 | Binding ≤ 10μM |
| CATG_HUMAN | P08311 | Cathepsin G, Human | 3000 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases | |
| Degradation of the extracellular matrix | |
| Metabolism of Angiotensinogen to Angiotensins | |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l |
