UCSF

Cathepsin G, Human (144 Compounds)

Swissprot:
CATG_HUMAN
Stitch:
CATG_HUMAN
UniProt:
P08311
ChEMBL:
CHEMBL4071
Reactome:
REACT_118682
REACT_118572
REACT_147707
REACT_15428
PDB:
1AU8 (DOCK)
1CGH (DOCK)
1KYN (DOCK)
1T32 (DOCK)
CTSG

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 144 3 0 5
Binding ≤ 1μM 86 1 0 1

Reactome Network (4)

Reactome ID Description Species
REACT_118682 Activation of Matrix Metalloproteinases Homo sapiens
REACT_118572 Degradation of the extracellular matrix Homo sapiens
REACT_147707 Metabolism of Angiotensinogen to Angiotensins Homo sapiens
REACT_15428 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CMA1_HUMAN P23946 CHEMBL4068 Chymase, Human 96
CTRB1_HUMAN P17538 CHEMBL4796 Beta-chymotrypsin, Human 44
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 12
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 41

Degradation of the extracellular matrix

Uniprot Swissprot Chembl Description Number Shared
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 2
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 2
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 12
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 1

Metabolism of Angiotensinogen to Angiotensins

Uniprot Swissprot Chembl Description Number Shared
CMA1_HUMAN P23946 CHEMBL4068 Chymase, Human 96

Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l

Uniprot Swissprot Chembl Description Number Shared
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 1
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 5
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CATG_MOUSE P28293 CHEMBL5622 Cathepsin G, Mouse 3 0 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CATG-1-E Cathepsin G (cluster #1 Of 2), Eukaryotic 141 2 0 5
CATG-2-E Cathepsin G (cluster #2 Of 2), Eukaryotic 3 1 0 0
Uniprot Swissprot Chembl Description Number Shared
CMA1_HUMAN P23946 CHEMBL4068 Chymase, Human 96
CEL2A_PIG P08419 CHEMBL2407 Elastase 2A, Pig 53
CTRB1_HUMAN P17538 CHEMBL4796 Beta-chymotrypsin, Human 44
CTRA_BOVIN P00766 CHEMBL3314 Alpha-chymotrypsin, Bovin 41
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 41
CTRB_BOVIN P00767 CHEMBL3063 Beta-chymotrypsin, Bovin 13
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 12
CMA1_RAT P50339 CHEMBL3168 Mast Cell Protease 3, Rat 6
CTRC_HUMAN Q99895 CHEMBL2386 Chymotrypsin C, Human 6
MCPT9_MOUSE O35164 CHEMBL2132 Mast Cell Protease 9, Mouse 6
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 5
ELNE_MOUSE Q3UP87 CHEMBL5156 Neutrophil Elastase, Mouse 4
PRTN3_MOUSE Q61096 CHEMBL5384 Myeloblastin, Mouse 4
CATC_HUMAN P53634 CHEMBL2252 Dipeptidyl Peptidase I, Human 3
CATG_MOUSE P28293 CHEMBL5622 Cathepsin G, Mouse 3
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 3
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 2
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 2
PPAP_HUMAN P15309 CHEMBL2633 Prostatic Acid Phosphatase, Human 2
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 1
PAPA1_CARPA P00784 CHEMBL4779 Papain, Carpa 1
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 1

Most Common Rings