UCSF

Chymase, Human (521 Compounds)

Swissprot:
CMA1_HUMAN
Stitch:
CMA1_HUMAN
UniProt:
P23946
ChEMBL:
CHEMBL4068
Reactome:
REACT_118682
REACT_147707
REACT_111040
PDB:
1KLT (DOCK)
1NN6 (DOCK)
1PJP (DOCK)
1T31 (DOCK)
2HVX (DOCK)
3N7O (DOCK)
3S0N (DOCK)
CMA1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 521 7 5 5
Binding ≤ 1μM 422 6 4 5
Uniprot Swissprot Chembl Description Number Shared
CATG_HUMAN P08311 CHEMBL4071 Cathepsin G, Human 96
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 3
CATL2_HUMAN O60911 CHEMBL3272 Cathepsin L2, Human 3
CTRB1_HUMAN P17538 CHEMBL4796 Beta-chymotrypsin, Human 32
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 4
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 1
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 34

Metabolism of Angiotensinogen to Angiotensins

Uniprot Swissprot Chembl Description Number Shared
CATG_HUMAN P08311 CHEMBL4071 Cathepsin G, Human 96
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CMA1_RAT P50339 CHEMBL3168 Mast Cell Protease 3, Rat 6 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CTRA_BOVIN P00766 CHEMBL3314 Alpha-chymotrypsin, Bovin 131
CATG_HUMAN P08311 CHEMBL4071 Cathepsin G, Human 96
CTRC_HUMAN Q99895 CHEMBL2386 Chymotrypsin C, Human 76
CEL2A_PIG P08419 CHEMBL2407 Elastase 2A, Pig 38
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 34
CTRB1_HUMAN P17538 CHEMBL4796 Beta-chymotrypsin, Human 32
CTRB_BOVIN P00767 CHEMBL3063 Beta-chymotrypsin, Bovin 9
CMA1_RAT P50339 CHEMBL3168 Mast Cell Protease 3, Rat 6
MCPT9_MOUSE O35164 CHEMBL2132 Mast Cell Protease 9, Mouse 6
ELNE_HUMAN P08246 CHEMBL248 Leukocyte Elastase, Human 4
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 4
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 3
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 3
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 3
CATL2_HUMAN O60911 CHEMBL3272 Cathepsin L2, Human 3
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 3
TRY1_BOVIN P00760 CHEMBL3769 Trypsin I, Bovin 3
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 3
A3EZI9_9HEPC A3EZI9 CHEMBL4893 Hepatitis C Virus NS3 Protease/helicase, 9hepc 2
CATF_HUMAN Q9UBX1 CHEMBL2517 Cathepsin F, Human 2
CELA1_HUMAN Q9UNI1 CHEMBL3000 Elastase 1, Human 1
D2K2A8_9HEPC D2K2A8 CHEMBL2364 Hepatitis C Virus NS4A Protein, 9hepc 1
PLMN_HUMAN P00747 CHEMBL1801 Plasminogen, Human 1
TRYP_PIG P00761 CHEMBL2366 Trypsin, Pig 1