| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 16th, 2008 | 31 | Yes |
Popular Name: 5-chloro-N-[2-(4-ethylpiperazin-1-yl)-4-methyl-6-quinolyl]-2-methoxy-benzamide 5-chloro-N-[2-(4-ethylpiperazin-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.41 | 12.56 | -45.9 | 2 | 6 | 1 | 59 | 439.967 | 5 | ↓ |
| Hi High (pH 8-9.5) | 5.41 | 10.35 | -13.28 | 1 | 6 | 0 | 58 | 438.959 | 5 | ↓ |
| Mid Mid (pH 6-8) | 5.41 | 10.65 | -30.3 | 2 | 6 | 1 | 59 | 439.967 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MCHR1-1-E | Melanin-concentrating Hormone Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2630 | 0.25 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 2630 | 0.25 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| G alpha (q) signalling events | |
| Peptide ligand-binding receptors |
