| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 7th, 2009 | 28 | Yes |
Popular Name: DNC007720 DNC007720
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.00 | 11.72 | -44.83 | 2 | 3 | 1 | 34 | 374.504 | 5 | ↓ |
| Hi High (pH 8-9.5) | 5.00 | 10.11 | -6.29 | 1 | 3 | 0 | 33 | 373.496 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRX-1-E | Nociceptin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 588 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| OPRX_HUMAN | P41146 | Nociceptin Receptor, Human | 588 | 0.31 | Binding ≤ 1μM |
| OPRX_HUMAN | P41146 | Nociceptin Receptor, Human | 588 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Peptide ligand-binding receptors |
