Note Type	Comments	Provided By
ALOGPS_SOLUBILITY	1.02e-02 g/l	DrugBank-approved
ALOGPS_SOLUBILITY	2.61e-03 g/l	DrugBank-experimental
Purity	>99%	Fluorochem
Patent Database Links	EP1977765; WO2007096393; WO2007096395	ChEBI
Reactome Database Links	REACT_115609	ChEBI
Target	VEGFR	Selleck Chemicals

Activity (Go SEA)

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
AAPK1-1-E	AMP-activated Protein Kinase, Alpha-1 Subunit (cluster #1 Of 1), Eukaryotic	Eukaryotes	10000	0.23	Binding ≤ 10μM
ABL1-1-E	Tyrosine-protein Kinase ABL (cluster #1 Of 1), Eukaryotic	Eukaryotes	94	0.33	Binding ≤ 10μM
ABL2-1-E	Tyrosine-protein Kinase ABL2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	69	0.33	Binding ≤ 10μM
ACVL1-1-E	Serine/threonine-protein Kinase Receptor R3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	470	0.30	Binding ≤ 10μM
ACVR1-1-E	Activin Receptor Type-1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	150	0.32	Binding ≤ 10μM
ADCK3-1-E	Chaperone Activity Of Bc1 Complex-like, Mitochondrial (cluster #1 Of 1), Eukaryotic	Eukaryotes	4500	0.25	Binding ≤ 10μM
ADCK4-1-E	Uncharacterized AarF Domain-containing Protein Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1700	0.27	Binding ≤ 10μM
ALK-1-E	ALK Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	2100	0.26	Binding ≤ 10μM
AURKC-1-E	Serine/threonine-protein Kinase Aurora-C (cluster #1 Of 2), Eukaryotic	Eukaryotes	1500	0.27	Binding ≤ 10μM
BLK-1-E	Tyrosine-protein Kinase BLK (cluster #1 Of 1), Eukaryotic	Eukaryotes	66	0.34	Binding ≤ 10μM
CSF1R-1-E	Macrophage Colony-stimulating Factor 1 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	1200	0.28	Binding ≤ 10μM
CSK-1-E	Tyrosine-protein Kinase CSK (cluster #1 Of 1), Eukaryotic	Eukaryotes	3700	0.25	Binding ≤ 10μM
CTRO-1-E	Citron Rho-interacting Kinase (cluster #1 Of 1), Eukaryotic	Eukaryotes	1800	0.27	Binding ≤ 10μM
DDR1-1-E	Epithelial Discoidin Domain-containing Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	11	0.37	Binding ≤ 10μM
DDR2-1-E	Discoidin Domain-containing Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	320	0.30	Binding ≤ 10μM
EGFR-3-E	Epidermal Growth Factor Receptor ErbB1 (cluster #3 Of 4), Eukaryotic	Eukaryotes	10	0.37	Binding ≤ 10μM
EGFR-3-E	Epidermal Growth Factor Receptor ErbB1 (cluster #3 Of 4), Eukaryotic	Eukaryotes	500	0.29	Binding ≤ 10μM
EPHA1-1-E	Ephrin Type-A Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	230	0.31	Binding ≤ 10μM
EPHA2-1-E	Ephrin Type-A Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1900	0.27	Binding ≤ 10μM
EPHA3-1-E	Ephrin Type-A Receptor 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	2000	0.27	Binding ≤ 10μM
EPHA4-1-E	Ephrin Type-A Receptor 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4300	0.25	Binding ≤ 10μM
EPHA5-1-E	Ephrin Type-A Receptor 5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	310	0.30	Binding ≤ 10μM
EPHA6-1-E	Ephrin Type-A Receptor 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	65	0.34	Binding ≤ 10μM
EPHA7-1-E	Ephrin Type-A Receptor 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3400	0.26	Binding ≤ 10μM
EPHA8-1-E	Ephrin Type-A Receptor 8 (cluster #1 Of 1), Eukaryotic	Eukaryotes	91	0.33	Binding ≤ 10μM
EPHB1-1-E	Ephrin Type-B Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	540	0.29	Binding ≤ 10μM
EPHB2-1-E	Ephrin Type-B Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	440	0.30	Binding ≤ 10μM
EPHB4-1-E	Ephrin Type-B Receptor 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	520	0.29	Binding ≤ 10μM
ERBB2-2-E	Receptor Protein-tyrosine Kinase ErbB-2 (cluster #2 Of 3), Eukaryotic	Eukaryotes	2600	0.26	Binding ≤ 10μM
FGFR1-1-E	Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	560	0.29	Binding ≤ 10μM
FGFR1-1-E	Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3600	0.25	Binding ≤ 10μM
FGFR2-1-E	Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5500	0.25	Binding ≤ 10μM
FGFR3-1-E	Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	6900	0.24	Binding ≤ 10μM
FGR-1-E	Tyrosine-protein Kinase FGR (cluster #1 Of 2), Eukaryotic	Eukaryotes	270	0.31	Binding ≤ 10μM
FLT3-1-E	Tyrosine-protein Kinase Receptor FLT3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	850	0.28	Binding ≤ 10μM
FRK-1-E	Tyrosine-protein Kinase FRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	480	0.29	Binding ≤ 10μM
FYN-1-E	Tyrosine-protein Kinase FYN (cluster #1 Of 5), Eukaryotic	Eukaryotes	5700	0.24	Binding ≤ 10μM
GAK-1-E	Serine/threonine-protein Kinase GAK (cluster #1 Of 2), Eukaryotic	Eukaryotes	86	0.33	Binding ≤ 10μM
HCK-1-E	Tyrosine-protein Kinase HCK (cluster #1 Of 1), Eukaryotic	Eukaryotes	4200	0.25	Binding ≤ 10μM
KC1E-1-E	Casein Kinase I Epsilon (cluster #1 Of 2), Eukaryotic	Eukaryotes	3000	0.26	Binding ≤ 10μM
KIT-1-E	Stem Cell Growth Factor Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	560	0.29	Binding ≤ 10μM
KS6A1-1-E	Ribosomal Protein S6 Kinase Alpha 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	400	0.30	Binding ≤ 10μM
KS6A6-1-E	Ribosomal Protein S6 Kinase Alpha 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	240	0.31	Binding ≤ 10μM
LCK-1-E	Tyrosine-protein Kinase LCK (cluster #1 Of 4), Eukaryotic	Eukaryotes	61	0.34	Binding ≤ 10μM
LTK-1-E	Leukocyte Tyrosine Kinase Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	550	0.29	Binding ≤ 10μM
LYN-1-E	Tyrosine-protein Kinase Lyn (cluster #1 Of 1), Eukaryotic	Eukaryotes	710	0.29	Binding ≤ 10μM
M3K4-1-E	Mitogen-activated Protein Kinase Kinase Kinase 4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	4800	0.25	Binding ≤ 10μM
M4K3-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1500	0.27	Binding ≤ 10μM
M4K4-2-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 4 (cluster #2 Of 2), Eukaryotic	Eukaryotes	1400	0.27	Binding ≤ 10μM
M4K5-1-E	Mitogen-activated Protein Kinase Kinase Kinase Kinase 5 (cluster #1 Of 1), Eukaryotic	Eukaryotes	510	0.29	Binding ≤ 10μM
MERTK-1-E	Proto-oncogene Tyrosine-protein Kinase MER (cluster #1 Of 1), Eukaryotic	Eukaryotes	1400	0.27	Binding ≤ 10μM
MET-1-E	Hepatocyte Growth Factor Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	5700	0.24	Binding ≤ 10μM
MK06-1-E	Mitogen-activated Protein Kinase 6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1500	0.27	Binding ≤ 10μM
MKNK1-1-E	MAP Kinase-interacting Serine/threonine-protein Kinase MNK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	360	0.30	Binding ≤ 10μM
MKNK2-1-E	MAP Kinase Signal-integrating Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3400	0.26	Binding ≤ 10μM
MLTK-1-E	Mixed Lineage Kinase 7 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5100	0.25	Binding ≤ 10μM
MP2K1-3-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 1 (cluster #3 Of 4), Eukaryotic	Eukaryotes	1800	0.27	Binding ≤ 10μM
MP2K2-1-E	Dual Specificity Mitogen-activated Protein Kinase Kinase 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1100	0.28	Binding ≤ 10μM
MRCKA-1-E	Serine/threonine-protein Kinase MRCK-A (cluster #1 Of 1), Eukaryotic	Eukaryotes	2600	0.26	Binding ≤ 10μM
MRCKB-1-E	Serine/threonine-protein Kinase MRCK Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	2500	0.26	Binding ≤ 10μM
MRCKG-1-E	Serine/threonine-protein Kinase MRCK Gamma (cluster #1 Of 1), Eukaryotic	Eukaryotes	2200	0.26	Binding ≤ 10μM
PGFRA-2-E	Platelet-derived Growth Factor Receptor Alpha (cluster #2 Of 2), Eukaryotic	Eukaryotes	230	0.31	Binding ≤ 10μM
PGFRB-1-E	Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	88	0.33	Binding ≤ 10μM
PGFRB-1-E	Platelet-derived Growth Factor Receptor Beta (cluster #1 Of 1), Eukaryotic	Eukaryotes	1100	0.28	Binding ≤ 10μM
PHKG1-1-E	Phosphorylase Kinase Gamma Subunit 1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	7100	0.24	Binding ≤ 10μM
PHKG2-1-E	Phosphorylase Kinase Gamma Subunit 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	9500	0.23	Binding ≤ 10μM
PLK4-1-E	Serine/threonine-protein Kinase PLK4 (cluster #1 Of 1), Eukaryotic	Eukaryotes	620	0.29	Binding ≤ 10μM
PTK6-1-E	Tyrosine-protein Kinase BRK (cluster #1 Of 1), Eukaryotic	Eukaryotes	33	0.35	Binding ≤ 10μM
RET-1-E	Tyrosine-protein Kinase Receptor RET (cluster #1 Of 1), Eukaryotic	Eukaryotes	97	0.33	Binding ≤ 10μM
RIPK2-1-E	Serine/threonine-protein Kinase RIPK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	5	0.39	Binding ≤ 10μM
SIK1-1-E	Serine/threonine-protein Kinase SIK1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1900	0.27	Binding ≤ 10μM
SIK2-1-E	Serine/threonine-protein Kinase SIK2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	430	0.30	Binding ≤ 10μM
SLK-1-E	Serine/threonine-protein Kinase 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	96	0.33	Binding ≤ 10μM
SRC-1-E	Tyrosine-protein Kinase SRC (cluster #1 Of 3), Eukaryotic	Eukaryotes	70	0.33	Binding ≤ 10μM
SRMS-1-E	Tyrosine-protein Kinase Srms (cluster #1 Of 1), Eukaryotic	Eukaryotes	1900	0.27	Binding ≤ 10μM
STK10-1-E	Serine/threonine-protein Kinase 10 (cluster #1 Of 1), Eukaryotic	Eukaryotes	81	0.33	Binding ≤ 10μM
STK33-1-E	Serine/threonine-protein Kinase 33 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1400	0.27	Binding ≤ 10μM
TBA1A-1-E	Tubulin Alpha-3 Chain (cluster #1 Of 3), Eukaryotic	Eukaryotes	480	0.29	Binding ≤ 10μM
TESK1-1-E	Dual Specificity Testis-specific Protein Kinase 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	3700	0.25	Binding ≤ 10μM
TIE1-1-E	Tyrosine-protein Kinase Receptor Tie-1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1500	0.27	Binding ≤ 10μM
TIE2-1-E	Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	2500	0.26	Binding ≤ 10μM
TIE2-1-E	Tyrosine-protein Kinase TIE-2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	3600	0.25	Binding ≤ 10μM
TNI3K-1-E	Serine/threonine-protein Kinase TNNI3K (cluster #1 Of 1), Eukaryotic	Eukaryotes	2800	0.26	Binding ≤ 10μM
TNIK-1-E	TRAF2- And NCK-interacting Kinase (cluster #1 Of 2), Eukaryotic	Eukaryotes	3900	0.25	Binding ≤ 10μM
TXK-1-E	Tyrosine-protein Kinase TXK (cluster #1 Of 1), Eukaryotic	Eukaryotes	3700	0.25	Binding ≤ 10μM
TYRO3-1-E	Tyrosine-protein Kinase Receptor TYRO3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	93	0.33	Binding ≤ 10μM
UFO-1-E	Tyrosine-protein Kinase Receptor UFO (cluster #1 Of 1), Eukaryotic	Eukaryotes	250	0.31	Binding ≤ 10μM
VGFR1-1-E	Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	260	0.31	Binding ≤ 10μM
VGFR1-1-E	Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1600	0.27	Binding ≤ 10μM
VGFR2-1-E	Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	9	0.38	Binding ≤ 10μM
VGFR2-1-E	Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	40	0.35	Binding ≤ 10μM
VGFR3-1-E	Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	300	0.30	Binding ≤ 10μM
YES-1-E	Tyrosine-protein Kinase YES (cluster #1 Of 1), Eukaryotic	Eukaryotes	280	0.31	Binding ≤ 10μM
EGFR-1-E	Epidermal Growth Factor Receptor ErbB1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	170	0.32	Functional ≤ 10μM
FGFR1-1-E	Fibroblast Growth Factor Receptor 1 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1200	0.28	Functional ≤ 10μM
FGFR2-1-E	Fibroblast Growth Factor Receptor 2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1200	0.28	Functional ≤ 10μM
FGFR3-1-E	Fibroblast Growth Factor Receptor 3 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1200	0.28	Functional ≤ 10μM
VGFR1-1-E	Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	60	0.34	Functional ≤ 10μM
VGFR1-1-E	Vascular Endothelial Growth Factor Receptor 1 (cluster #1 Of 2), Eukaryotic	Eukaryotes	400	0.30	Functional ≤ 10μM
VGFR2-1-E	Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	60	0.34	Functional ≤ 10μM
VGFR2-1-E	Vascular Endothelial Growth Factor Receptor 2 (cluster #1 Of 2), Eukaryotic	Eukaryotes	400	0.30	Functional ≤ 10μM
VGFR3-1-E	Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	60	0.34	Functional ≤ 10μM
VGFR3-1-E	Vascular Endothelial Growth Factor Receptor 3 (cluster #1 Of 2), Eukaryotic	Eukaryotes	400	0.30	Functional ≤ 10μM
Z100768-1-O	TPC1 (Papillary Thyroid Carinoma Cells) (cluster #1 Of 1), Other	Other	116	0.32	Functional ≤ 10μM
Z80166-1-O	HT-29 (Colon Adenocarcinoma Cells) (cluster #1 Of 12), Other	Other	4200	0.25	Functional ≤ 10μM
Z81057-1-O	HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other	Other	60	0.34	Functional ≤ 10μM
Z81057-1-O	HUVEC (Umbilical Vein Endothelial Cells) (cluster #1 Of 4), Other	Other	400	0.30	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
ACVR1_HUMAN	Q04771	Activin Receptor Type-1, Human	150	0.32	Binding ≤ 1μM
DDR2_HUMAN	Q16832	Discoidin Domain-containing Receptor 2, Human	320	0.30	Binding ≤ 1μM
EPHA1_HUMAN	P21709	Ephrin Type-A Receptor 1, Human	230	0.31	Binding ≤ 1μM
EPHA5_HUMAN	P54756	Ephrin Type-A Receptor 5, Human	240	0.31	Binding ≤ 1μM
EPHA6_HUMAN	Q9UF33	Ephrin Type-A Receptor 6, Human	50	0.34	Binding ≤ 1μM
EPHA8_HUMAN	P29322	Ephrin Type-A Receptor 8, Human	160	0.32	Binding ≤ 1μM
EPHB1_HUMAN	P54762	Ephrin Type-B Receptor 1, Human	290	0.31	Binding ≤ 1μM
EPHB2_HUMAN	P29323	Ephrin Type-B Receptor 2, Human	440	0.30	Binding ≤ 1μM
EPHB4_HUMAN	P54760	Ephrin Type-B Receptor 4, Human	520	0.29	Binding ≤ 1μM
EGFR_HUMAN	P00533	Epidermal Growth Factor Receptor ErbB1, Human	11	0.37	Binding ≤ 1μM
DDR1_HUMAN	Q08345	Epithelial Discoidin Domain-containing Receptor 1, Human	11	0.37	Binding ≤ 1μM
FGFR1_HUMAN	P11362	Fibroblast Growth Factor Receptor 1, Human	560	0.29	Binding ≤ 1μM
FGFR3_HUMAN	P22607	Fibroblast Growth Factor Receptor 3, Human	240	0.31	Binding ≤ 1μM
LTK_HUMAN	P29376	Leukocyte Tyrosine Kinase Receptor, Human	550	0.29	Binding ≤ 1μM
MKNK1_HUMAN	Q9BUB5	MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human	360	0.30	Binding ≤ 1μM
M4K5_HUMAN	Q9Y4K4	Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human	450	0.30	Binding ≤ 1μM
PGFRA_HUMAN	P16234	Platelet-derived Growth Factor Receptor Alpha, Human	230	0.31	Binding ≤ 1μM
PGFRB_HUMAN	P09619	Platelet-derived Growth Factor Receptor Beta, Human	250	0.31	Binding ≤ 1μM
KS6A1_HUMAN	Q15418	Ribosomal Protein S6 Kinase Alpha 1, Human	400	0.30	Binding ≤ 1μM
KS6A6_HUMAN	Q9UK32	Ribosomal Protein S6 Kinase Alpha 6, Human	240	0.31	Binding ≤ 1μM
STK10_HUMAN	O94804	Serine/threonine-protein Kinase 10, Human	81	0.33	Binding ≤ 1μM
SLK_HUMAN	Q9H2G2	Serine/threonine-protein Kinase 2, Human	95	0.33	Binding ≤ 1μM
GAK_HUMAN	O14976	Serine/threonine-protein Kinase GAK, Human	330	0.30	Binding ≤ 1μM
PLK4_HUMAN	O00444	Serine/threonine-protein Kinase PLK4, Human	620	0.29	Binding ≤ 1μM
ACVL1_HUMAN	P37023	Serine/threonine-protein Kinase Receptor R3, Human	470	0.30	Binding ≤ 1μM
RIPK2_HUMAN	O43353	Serine/threonine-protein Kinase RIPK2, Human	31	0.35	Binding ≤ 1μM
SIK2_HUMAN	Q9H0K1	Serine/threonine-protein Kinase SIK2, Human	430	0.30	Binding ≤ 1μM
KIT_HUMAN	P10721	Stem Cell Growth Factor Receptor, Human	180	0.31	Binding ≤ 1μM
TBA1A_RAT	P68370	Tubulin Alpha-1 Chain, Rat	480	0.29	Binding ≤ 1μM
ABL1_HUMAN	P00519	Tyrosine-protein Kinase ABL, Human	100	0.33	Binding ≤ 1μM
ABL2_HUMAN	P42684	Tyrosine-protein Kinase ABL2, Human	130	0.32	Binding ≤ 1μM
BLK_HUMAN	P51451	Tyrosine-protein Kinase BLK, Human	66	0.34	Binding ≤ 1μM
PTK6_HUMAN	Q13882	Tyrosine-protein Kinase BRK, Human	160	0.32	Binding ≤ 1μM
FGR_HUMAN	P09769	Tyrosine-protein Kinase FGR, Human	270	0.31	Binding ≤ 1μM
FRK_HUMAN	P42685	Tyrosine-protein Kinase FRK, Human	170	0.32	Binding ≤ 1μM
FYN_HUMAN	P06241	Tyrosine-protein Kinase FYN, Human	360	0.30	Binding ≤ 1μM
HCK_HUMAN	P08631	Tyrosine-protein Kinase HCK, Human	360	0.30	Binding ≤ 1μM
LCK_HUMAN	P06239	Tyrosine-protein Kinase LCK, Human	17	0.36	Binding ≤ 1μM
LYN_HUMAN	P07948	Tyrosine-protein Kinase Lyn, Human	110	0.32	Binding ≤ 1μM
FLT3_HUMAN	P36888	Tyrosine-protein Kinase Receptor FLT3, Human	560	0.29	Binding ≤ 1μM
RET_HUMAN	P07949	Tyrosine-protein Kinase Receptor RET, Human	14	0.37	Binding ≤ 1μM
TYRO3_HUMAN	Q06418	Tyrosine-protein Kinase Receptor TYRO3, Human	93	0.33	Binding ≤ 1μM
UFO_HUMAN	P30530	Tyrosine-protein Kinase Receptor UFO, Human	250	0.31	Binding ≤ 1μM
SRC_HUMAN	P12931	Tyrosine-protein Kinase SRC, Human	170	0.32	Binding ≤ 1μM
TIE2_HUMAN	Q02763	Tyrosine-protein Kinase TIE-2, Human	1000	0.28	Binding ≤ 1μM
YES_HUMAN	P07947	Tyrosine-protein Kinase YES, Human	120	0.32	Binding ≤ 1μM
VGFR1_HUMAN	P17948	Vascular Endothelial Growth Factor Receptor 1, Human	100	0.33	Binding ≤ 1μM
VGFR2_HUMAN	P35968	Vascular Endothelial Growth Factor Receptor 2, Human	100	0.33	Binding ≤ 1μM
VGFR3_HUMAN	P35916	Vascular Endothelial Growth Factor Receptor 3, Human	300	0.30	Binding ≤ 1μM
ACVR1_HUMAN	Q04771	Activin Receptor Type-1, Human	150	0.32	Binding ≤ 10μM
ALK_HUMAN	Q9UM73	ALK Tyrosine Kinase Receptor, Human	2100	0.26	Binding ≤ 10μM
AAPK1_HUMAN	Q13131	AMP-activated Protein Kinase, Alpha-1 Subunit, Human	10000	0.23	Binding ≤ 10μM
KC1E_HUMAN	P49674	Casein Kinase I Epsilon, Human	1500	0.27	Binding ≤ 10μM
ADCK3_HUMAN	Q8NI60	Chaperone Activity Of Bc1 Complex-like, Mitochondrial, Human	4500	0.25	Binding ≤ 10μM
CTRO_HUMAN	O14578	Citron Rho-interacting Kinase, Human	1800	0.27	Binding ≤ 10μM
DDR2_HUMAN	Q16832	Discoidin Domain-containing Receptor 2, Human	320	0.30	Binding ≤ 10μM
MP2K1_HUMAN	Q02750	Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human	1800	0.27	Binding ≤ 10μM
MP2K2_HUMAN	P36507	Dual Specificity Mitogen-activated Protein Kinase Kinase 2, Human	1100	0.28	Binding ≤ 10μM
TESK1_HUMAN	Q15569	Dual Specificity Testis-specific Protein Kinase 1, Human	3700	0.25	Binding ≤ 10μM
EPHA1_HUMAN	P21709	Ephrin Type-A Receptor 1, Human	230	0.31	Binding ≤ 10μM
EPHA2_HUMAN	P29317	Ephrin Type-A Receptor 2, Human	1100	0.28	Binding ≤ 10μM
EPHA3_HUMAN	P29320	Ephrin Type-A Receptor 3, Human	1800	0.27	Binding ≤ 10μM
EPHA4_HUMAN	P54764	Ephrin Type-A Receptor 4, Human	1600	0.27	Binding ≤ 10μM
EPHA5_HUMAN	P54756	Ephrin Type-A Receptor 5, Human	240	0.31	Binding ≤ 10μM
EPHA6_HUMAN	Q9UF33	Ephrin Type-A Receptor 6, Human	50	0.34	Binding ≤ 10μM
EPHA7_HUMAN	Q15375	Ephrin Type-A Receptor 7, Human	2400	0.26	Binding ≤ 10μM
EPHA8_HUMAN	P29322	Ephrin Type-A Receptor 8, Human	160	0.32	Binding ≤ 10μM
EPHB1_HUMAN	P54762	Ephrin Type-B Receptor 1, Human	290	0.31	Binding ≤ 10μM
EPHB2_HUMAN	P29323	Ephrin Type-B Receptor 2, Human	440	0.30	Binding ≤ 10μM
EPHB4_HUMAN	P54760	Ephrin Type-B Receptor 4, Human	2600	0.26	Binding ≤ 10μM
EGFR_HUMAN	P00533	Epidermal Growth Factor Receptor ErbB1, Human	11	0.37	Binding ≤ 10μM
DDR1_HUMAN	Q08345	Epithelial Discoidin Domain-containing Receptor 1, Human	11	0.37	Binding ≤ 10μM
FGFR1_HUMAN	P11362	Fibroblast Growth Factor Receptor 1, Human	5300	0.25	Binding ≤ 10μM
FGFR2_HUMAN	P21802	Fibroblast Growth Factor Receptor 2, Human	1100	0.28	Binding ≤ 10μM
FGFR3_HUMAN	P22607	Fibroblast Growth Factor Receptor 3, Human	1600	0.27	Binding ≤ 10μM
MET_HUMAN	P08581	Hepatocyte Growth Factor Receptor, Human	5700	0.24	Binding ≤ 10μM
LTK_HUMAN	P29376	Leukocyte Tyrosine Kinase Receptor, Human	550	0.29	Binding ≤ 10μM
CSF1R_HUMAN	P07333	Macrophage Colony Stimulating Factor Receptor, Human	1200	0.28	Binding ≤ 10μM
MKNK2_HUMAN	Q9HBH9	MAP Kinase Signal-integrating Kinase 2, Human	1700	0.27	Binding ≤ 10μM
MKNK1_HUMAN	Q9BUB5	MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human	360	0.30	Binding ≤ 10μM
MK06_HUMAN	Q16659	Mitogen-activated Protein Kinase 6, Human	1500	0.27	Binding ≤ 10μM
M3K4_HUMAN	Q9Y6R4	Mitogen-activated Protein Kinase Kinase Kinase 4, Human	4800	0.25	Binding ≤ 10μM
M4K3_HUMAN	Q8IVH8	Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human	1500	0.27	Binding ≤ 10μM
M4K4_HUMAN	O95819	Mitogen-activated Protein Kinase Kinase Kinase Kinase 4, Human	1400	0.27	Binding ≤ 10μM
M4K5_HUMAN	Q9Y4K4	Mitogen-activated Protein Kinase Kinase Kinase Kinase 5, Human	450	0.30	Binding ≤ 10μM
MLTK_HUMAN	Q9NYL2	Mixed Lineage Kinase 7, Human	5100	0.25	Binding ≤ 10μM
PHKG1_HUMAN	Q16816	Phosphorylase Kinase Gamma Subunit 1, Human	1100	0.28	Binding ≤ 10μM
PHKG2_HUMAN	P15735	Phosphorylase Kinase Gamma Subunit 2, Human	9500	0.23	Binding ≤ 10μM
PGFRA_HUMAN	P16234	Platelet-derived Growth Factor Receptor Alpha, Human	230	0.31	Binding ≤ 10μM
PGFRB_HUMAN	P09619	Platelet-derived Growth Factor Receptor Beta, Human	250	0.31	Binding ≤ 10μM
MERTK_HUMAN	Q12866	Proto-oncogene Tyrosine-protein Kinase MER, Human	1400	0.27	Binding ≤ 10μM
ERBB2_HUMAN	P04626	Receptor Protein-tyrosine Kinase ErbB-2, Human	2600	0.26	Binding ≤ 10μM
KS6A1_HUMAN	Q15418	Ribosomal Protein S6 Kinase Alpha 1, Human	400	0.30	Binding ≤ 10μM
KS6A6_HUMAN	Q9UK32	Ribosomal Protein S6 Kinase Alpha 6, Human	240	0.31	Binding ≤ 10μM
STK10_HUMAN	O94804	Serine/threonine-protein Kinase 10, Human	2400	0.26	Binding ≤ 10μM
SLK_HUMAN	Q9H2G2	Serine/threonine-protein Kinase 2, Human	95	0.33	Binding ≤ 10μM
STK33_HUMAN	Q9BYT3	Serine/threonine-protein Kinase 33, Human	1400	0.27	Binding ≤ 10μM
AURKC_HUMAN	Q9UQB9	Serine/threonine-protein Kinase Aurora-C, Human	1500	0.27	Binding ≤ 10μM
GAK_HUMAN	O14976	Serine/threonine-protein Kinase GAK, Human	330	0.30	Binding ≤ 10μM
MRCKB_HUMAN	Q9Y5S2	Serine/threonine-protein Kinase MRCK Beta, Human	2500	0.26	Binding ≤ 10μM
MRCKG_HUMAN	Q6DT37	Serine/threonine-protein Kinase MRCK Gamma, Human	2200	0.26	Binding ≤ 10μM
MRCKA_HUMAN	Q5VT25	Serine/threonine-protein Kinase MRCK-A, Human	2600	0.26	Binding ≤ 10μM
PLK4_HUMAN	O00444	Serine/threonine-protein Kinase PLK4, Human	1500	0.27	Binding ≤ 10μM
ACVL1_HUMAN	P37023	Serine/threonine-protein Kinase Receptor R3, Human	470	0.30	Binding ≤ 10μM
RIPK2_HUMAN	O43353	Serine/threonine-protein Kinase RIPK2, Human	31	0.35	Binding ≤ 10μM
SIK1_HUMAN	P57059	Serine/threonine-protein Kinase SIK1, Human	1900	0.27	Binding ≤ 10μM
SIK2_HUMAN	Q9H0K1	Serine/threonine-protein Kinase SIK2, Human	430	0.30	Binding ≤ 10μM
TNI3K_HUMAN	Q59H18	Serine/threonine-protein Kinase TNNI3K, Human	2800	0.26	Binding ≤ 10μM
KIT_HUMAN	P10721	Stem Cell Growth Factor Receptor, Human	1100	0.28	Binding ≤ 10μM
TNIK_HUMAN	Q9UKE5	TRAF2- And NCK-interacting Kinase, Human	2300	0.26	Binding ≤ 10μM
TBA1A_RAT	P68370	Tubulin Alpha-1 Chain, Rat	480	0.29	Binding ≤ 10μM
ABL1_HUMAN	P00519	Tyrosine-protein Kinase ABL, Human	100	0.33	Binding ≤ 10μM
ABL2_HUMAN	P42684	Tyrosine-protein Kinase ABL2, Human	130	0.32	Binding ≤ 10μM
BLK_HUMAN	P51451	Tyrosine-protein Kinase BLK, Human	66	0.34	Binding ≤ 10μM
PTK6_HUMAN	Q13882	Tyrosine-protein Kinase BRK, Human	160	0.32	Binding ≤ 10μM
CSK_HUMAN	P41240	Tyrosine-protein Kinase CSK, Human	2500	0.26	Binding ≤ 10μM
FGR_HUMAN	P09769	Tyrosine-protein Kinase FGR, Human	2200	0.26	Binding ≤ 10μM
FRK_HUMAN	P42685	Tyrosine-protein Kinase FRK, Human	170	0.32	Binding ≤ 10μM
FYN_HUMAN	P06241	Tyrosine-protein Kinase FYN, Human	360	0.30	Binding ≤ 10μM
HCK_HUMAN	P08631	Tyrosine-protein Kinase HCK, Human	360	0.30	Binding ≤ 10μM
LCK_HUMAN	P06239	Tyrosine-protein Kinase LCK, Human	17	0.36	Binding ≤ 10μM
LYN_HUMAN	P07948	Tyrosine-protein Kinase Lyn, Human	110	0.32	Binding ≤ 10μM
FLT3_HUMAN	P36888	Tyrosine-protein Kinase Receptor FLT3, Human	1200	0.28	Binding ≤ 10μM
RET_HUMAN	P07949	Tyrosine-protein Kinase Receptor RET, Human	14	0.37	Binding ≤ 10μM
TIE1_HUMAN	P35590	Tyrosine-protein Kinase Receptor Tie-1, Human	1500	0.27	Binding ≤ 10μM
TYRO3_HUMAN	Q06418	Tyrosine-protein Kinase Receptor TYRO3, Human	93	0.33	Binding ≤ 10μM
UFO_HUMAN	P30530	Tyrosine-protein Kinase Receptor UFO, Human	250	0.31	Binding ≤ 10μM
SRC_HUMAN	P12931	Tyrosine-protein Kinase SRC, Human	170	0.32	Binding ≤ 10μM
SRMS_HUMAN	Q9H3Y6	Tyrosine-protein Kinase Srms, Human	1900	0.27	Binding ≤ 10μM
TIE2_HUMAN	Q02763	Tyrosine-protein Kinase TIE-2, Human	1000	0.28	Binding ≤ 10μM
TXK_HUMAN	P42681	Tyrosine-protein Kinase TXK, Human	3700	0.25	Binding ≤ 10μM
YES_HUMAN	P07947	Tyrosine-protein Kinase YES, Human	120	0.32	Binding ≤ 10μM
ADCK4_HUMAN	Q96D53	Uncharacterized AarF Domain-containing Protein Kinase 4, Human	1700	0.27	Binding ≤ 10μM
VGFR1_HUMAN	P17948	Vascular Endothelial Growth Factor Receptor 1, Human	100	0.33	Binding ≤ 10μM
VGFR2_HUMAN	P35968	Vascular Endothelial Growth Factor Receptor 2, Human	100	0.33	Binding ≤ 10μM
VGFR3_HUMAN	P35916	Vascular Endothelial Growth Factor Receptor 3, Human	1100	0.28	Binding ≤ 10μM
EGFR_HUMAN	P00533	Epidermal Growth Factor Receptor ErbB1, Human	170	0.32	Functional ≤ 10μM
FGFR1_HUMAN	P11362	Fibroblast Growth Factor Receptor 1, Human	1200	0.28	Functional ≤ 10μM
FGFR2_HUMAN	P21802	Fibroblast Growth Factor Receptor 2, Human	1200	0.28	Functional ≤ 10μM
FGFR3_HUMAN	P22607	Fibroblast Growth Factor Receptor 3, Human	1200	0.28	Functional ≤ 10μM
Z80166	Z80166	HT-29 (Colon Adenocarcinoma Cells)	4200	0.25	Functional ≤ 10μM
Z81057	Z81057	HUVEC (Umbilical Vein Endothelial Cells)	400	0.30	Functional ≤ 10μM
Z100768	Z100768	TPC1 (Papillary Thyroid Carinoma Cells)	116	0.32	Functional ≤ 10μM
VGFR1_HUMAN	P17948	Vascular Endothelial Growth Factor Receptor 1, Human	400	0.30	Functional ≤ 10μM
VGFR2_HUMAN	P35968	Vascular Endothelial Growth Factor Receptor 2, Human	1660	0.27	Functional ≤ 10μM
VGFR3_HUMAN	P35916	Vascular Endothelial Growth Factor Receptor 3, Human	400	0.30	Functional ≤ 10μM

Direct Reactome Annotations (via ChEBI)

Description	Species
Signaling by constitutively active EGFR	Rattus norvegicus Sus scrofa Homo sapiens Xenopus tropicalis Taeniopygia guttata Bos taurus Danio rerio Caenorhabditis elegans Drosophila melanogaster Mus musculus Canis familiaris Gallus gallus

Reactome Annotations from Targets (via Uniprot)

Description	Species
Activated point mutants of FGFR2	Homo sapiens (FGFR2_HUMAN)
activated TAK1 mediates p38 MAPK activation	Homo sapiens (RIPK2_HUMAN)
Antigen activates B Cell Receptor (BCR) leading to generation of second messenge	Homo sapiens (FYN_HUMAN)
CD28 co-stimulation	Homo sapiens (LCK_HUMAN)
CD28 dependent PI3K/Akt signaling	Homo sapiens (LCK_HUMAN)
CD28 dependent Vav1 pathway	Homo sapiens (LCK_HUMAN)
CDO in myogenesis	Homo sapiens (ABL1_HUMAN)
Cell surface interactions at the vascular wall	Homo sapiens (FYN_HUMAN)
Circadian Clock	Homo sapiens (KC1E_HUMAN)
Constitutive PI3K/AKT Signaling in Cancer	Homo sapiens (EGFR_HUMAN)
CREB phosphorylation	Homo sapiens (KS6A1_HUMAN)
CREB phosphorylation through the activation of Ras	Homo sapiens (KS6A1_HUMAN)
CRMPs in Sema3A signaling	Homo sapiens (FYN_HUMAN)
CTLA4 inhibitory signaling	Homo sapiens (LCK_HUMAN)
DAP12 signaling	Homo sapiens (LCK_HUMAN)
DCC mediated attractive signaling	Homo sapiens (FYN_HUMAN)
Downregulation of ERBB2:ERBB3 signaling	Homo sapiens (ERBB2_HUMAN)
Downstream signal transduction	Homo sapiens (PGFRB_HUMAN)
Downstream TCR signaling	Homo sapiens (RIPK2_HUMAN)
EGFR downregulation	Homo sapiens (EGFR_HUMAN)
EGFR interacts with phospholipase C-gamma	Homo sapiens (EGFR_HUMAN)
EGFR Transactivation by Gastrin	Homo sapiens (EGFR_HUMAN)
EPH-ephrin mediated repulsion of cells	Homo sapiens (FYN_HUMAN)
EPH-Ephrin signaling	Homo sapiens (FYN_HUMAN)
EPHA-mediated growth cone collapse	Homo sapiens (FYN_HUMAN)
EPHB-mediated forward signaling	Homo sapiens (FYN_HUMAN)
Ephrin signaling	Homo sapiens (FYN_HUMAN)
ERK/MAPK targets	Homo sapiens (KS6A1_HUMAN)
ERK1 activation	Homo sapiens (MP2K1_HUMAN)
ERK2 activation	Homo sapiens (MP2K2_HUMAN)
Factors involved in megakaryocyte development and platelet production	Homo sapiens (ABL1_HUMAN)
Fc epsilon receptor (FCERI) signaling	Homo sapiens (LYN_HUMAN)
FCERI mediated Ca+2 mobilization	Homo sapiens (LYN_HUMAN)
FCERI mediated MAPK activation	Homo sapiens (LYN_HUMAN)
FCERI mediated NF-kB activation	Homo sapiens (LYN_HUMAN)
FCGR activation	Homo sapiens (FYN_HUMAN)
Formation of tubulin folding intermediates by CCT/TriC	Rattus norvegicus (TBA1A_RAT)
GAB1 signalosome	Homo sapiens (EGFR_HUMAN)
Gap junction assembly	Rattus norvegicus (TBA1A_RAT)
Gastrin-CREB signalling pathway via PKC and MAPK	Homo sapiens (KS6A1_HUMAN)
Generation of second messenger molecules	Homo sapiens (LCK_HUMAN)
Glycogen breakdown (glycogenolysis)	Homo sapiens (PHKG2_HUMAN)
Golgi Associated Vesicle Biogenesis	Homo sapiens (GAK_HUMAN)
GPVI-mediated activation cascade	Homo sapiens (LCK_HUMAN)
GRB2 events in EGFR signaling	Homo sapiens (EGFR_HUMAN)
GRB2 events in ERBB2 signaling	Homo sapiens (EGFR_HUMAN)
GRB7 events in ERBB2 signaling	Homo sapiens (ERBB2_HUMAN)
Growth hormone receptor signaling	Homo sapiens (LYN_HUMAN)
Integrin alphaIIb beta3 signaling	Homo sapiens (CSK_HUMAN)
Integrin cell surface interactions	Homo sapiens (VGFR2_HUMAN)
Interleukin-1 signaling	Homo sapiens (RIPK2_HUMAN)
Interleukin-2 signaling	Homo sapiens (LCK_HUMAN)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human	Homo sapiens (RIPK2_HUMAN)
Kinesins	Rattus norvegicus (TBA1A_RAT)
L1CAM interactions	Homo sapiens (EPHB2_HUMAN)
Loss of Nlp from mitotic centrosomes	Rattus norvegicus (TBA1A_RAT) Homo sapiens (PLK4_HUMAN)
Loss of proteins required for interphase microtubule organizationÂ from the ce	Rattus norvegicus (TBA1A_RAT) Homo sapiens (PLK4_HUMAN)
MEK activation	Homo sapiens (MP2K2_HUMAN)
MHC class II antigen presentation	Rattus norvegicus (TBA1A_RAT)
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	Rattus norvegicus (TBA1A_RAT)
Mitotic Prometaphase	Rattus norvegicus (TBA1A_RAT)
NCAM signaling for neurite out-growth	Homo sapiens (FYN_HUMAN)
Nef and signal transduction	Homo sapiens (LCK_HUMAN)
Nef Mediated CD4 Down-regulation	Homo sapiens (LCK_HUMAN)
Nephrin interactions	Homo sapiens (FYN_HUMAN)
Netrin mediated repulsion signals	Homo sapiens (FYN_HUMAN)
Neurophilin interactions with VEGF and VEGFR	Homo sapiens (VGFR1_HUMAN)
NOD1/2 Signaling Pathway	Homo sapiens (RIPK2_HUMAN)
Non-integrin membrane-ECM interactions	Homo sapiens (DDR1_HUMAN)
Oxidative Stress Induced Senescence	Homo sapiens (M4K4_HUMAN)
p75NTR recruits signalling complexes	Homo sapiens (RIPK2_HUMAN)
PD-1 signaling	Homo sapiens (LCK_HUMAN)
PECAM1 interactions	Homo sapiens (LCK_HUMAN)
Phosphorylation of CD3 and TCR zeta chains	Homo sapiens (LCK_HUMAN)
PI3K events in ERBB2 signaling	Homo sapiens (EGFR_HUMAN)
PIP3 activates AKT signaling	Homo sapiens (EGFR_HUMAN)
Platelet Adhesion to exposed collagen	Homo sapiens (FYN_HUMAN)
Platelet sensitization by LDL	Homo sapiens (FGR_HUMAN)
PLCG1 events in ERBB2 signaling	Homo sapiens (EGFR_HUMAN)
Post-chaperonin tubulin folding pathway	Rattus norvegicus (TBA1A_RAT)
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	Homo sapiens (EPHA1_HUMAN)
Prefoldin mediated transfer of substrate to CCT/TriC	Rattus norvegicus (TBA1A_RAT)
RAF phosphorylates MEK	Homo sapiens (MP2K2_HUMAN)
Recruitment of mitotic centrosome proteins and complexes	Homo sapiens (PLK4_HUMAN) Rattus norvegicus (TBA1A_RAT)
Recruitment of NuMA to mitotic centrosomes	Rattus norvegicus (TBA1A_RAT)
Recycling pathway of L1	Rattus norvegicus (TBA1A_RAT) Homo sapiens (KS6A1_HUMAN)
Regulation of actin dynamics for phagocytic cup formation	Homo sapiens (ABL1_HUMAN)
Regulation of AMPK activity via LKB1	Homo sapiens (AAPK1_HUMAN)
Regulation of cytoskeletal remodeling and cell spreading by IPP complex componen	Homo sapiens (TESK1_HUMAN)
Regulation of KIT signaling	Homo sapiens (LCK_HUMAN)
Regulation of PLK1 Activity at G2/M Transition	Homo sapiens (PLK4_HUMAN) Rattus norvegicus (TBA1A_RAT)
Regulation of Rheb GTPase activity by AMPK	Homo sapiens (AAPK1_HUMAN)
Regulation of signaling by CBL	Homo sapiens (FYN_HUMAN)
Resolution of Sister Chromatid Cohesion	Rattus norvegicus (TBA1A_RAT)
Role of Abl in Robo-Slit signaling	Homo sapiens (ABL1_HUMAN)
Role of LAT2/NTAL/LAB on calcium mobilization	Homo sapiens (FYN_HUMAN)
RSK activation	Homo sapiens (KS6A1_HUMAN)
Sema3A PAK dependent Axon repulsion	Homo sapiens (FYN_HUMAN)
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	Homo sapiens (FYN_HUMAN)
Sema4D induced cell migration and growth-cone collapse	Homo sapiens (ERBB2_HUMAN)
Sema4D mediated inhibition of cell attachment and migration	Homo sapiens (MET_HUMAN)
Senescence-Associated Secretory Phenotype (SASP)	Homo sapiens (KS6A1_HUMAN)
Separation of Sister Chromatids	Rattus norvegicus (TBA1A_RAT)
SHC1 events in EGFR signaling	Homo sapiens (EGFR_HUMAN)
SHC1 events in ERBB2 signaling	Homo sapiens (EGFR_HUMAN)
Signal transduction by L1	Homo sapiens (EGFR_HUMAN)
Signaling by activated point mutants of FGFR1	Homo sapiens (FGFR1_HUMAN)
Signaling by activated point mutants of FGFR3	Homo sapiens (FGFR3_HUMAN)
Signaling by constitutively active EGFR	Homo sapiens (EGFR_HUMAN)
Signaling by EGFR	Homo sapiens (EGFR_HUMAN)
Signaling by ERBB2	Homo sapiens (EGFR_HUMAN)
Signaling by ERBB4	Homo sapiens (EGFR_HUMAN)
Signaling by FGFR	Homo sapiens (MP2K2_HUMAN)
Signaling by FGFR mutants	Homo sapiens (FGFR1_HUMAN)
Signaling by FGFR2 amplification mutants	Homo sapiens (FGFR2_HUMAN)
Signaling by FGFR3 mutants	Homo sapiens (FGFR3_HUMAN)
Signaling by PDGF	Homo sapiens (PGFRB_HUMAN)
Signaling by SCF-KIT	Homo sapiens (LCK_HUMAN)
Spry regulation of FGF signaling	Homo sapiens (MKNK1_HUMAN)
t(4;14) translocations of FGFR3	Homo sapiens (FGFR3_HUMAN)
TAK1 activates NFkB by phosphorylation and activation of IKKs complex	Homo sapiens (RIPK2_HUMAN)
Tie2 Signaling	Homo sapiens (TIE2_HUMAN)
Translocation of GLUT4 to the plasma membrane	Rattus norvegicus (TBA1A_RAT)
Translocation of ZAP-70 to Immunological synapse	Homo sapiens (LCK_HUMAN)
Uptake and function of anthrax toxins	Homo sapiens (MP2K2_HUMAN)
VEGF binds to VEGFR leading to receptor dimerization	Homo sapiens (VGFR1_HUMAN)
VEGFA-VEGFR2 Pathway	Homo sapiens (FYN_HUMAN)
VEGFR2 mediated cell proliferation	Homo sapiens (VGFR2_HUMAN)
WNT mediated activation of DVL	Homo sapiens (KC1E_HUMAN)

Analogs ( Draw Identity 99% 90% 80% 70% )

3988508

Synonyms (68)
Vendors (32)
Annotations (19)
Representations (1)
Notes (6)
Targets (146)
Clustered (107)
Reactome (129)
Rings (0)
Analogs (1)