| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 4th, 2005 | 25 | Yes |
Popular Name: Lomefloxacin hydrochloride Lomefloxacin hydrochloride
Find On: PubMed — Wikipedia — Google
CAS Numbers: 114394-67-1 , 211690-33-4 , 98079-51-7 , 98079-52-8 , 98079-52-8, 98079-51-7 (l , 98079-52-8, 98079-51-7 (lomefloxacin) , [211690-33-4] , [98079-52-8]
(+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-
(+-)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1,4-Dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
1-ethyl-6,8-difluoro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid hydrochloride
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid hydrochloride
1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
114394-67-1; D02541; Lomefloxacin mesylate (USAN)
3-Quinolinecarboxylic acid, 1,4-dihydro-6,8-difluoro-1-ethyl-7-(3-methyl-1-piperazinyl)-4-oxo-
3-Quinolinecarboxylic acid, 1-ethyl-6,8-difluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo- (+/-)
98079-51-7; D02318; LFLX; Lomefloxacin (USAN)
98079-52-8; C08053; Lomefloxacin hydrochloride
98079-52-8; Lomefloxacin hydrochloride; Prestwick_581
FDA); Lomefloxacin Mesylate (USAN)
Lomefloxacin hydrochloride (Maxaquin)
SC-47111A; NY-198; SC-47111; SC-47111B
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.08 | 9.21 | -91.57 | 2 | 6 | 0 | 82 | 351.353 | 3 | ↓ |
| Hi High (pH 8-9.5) | 0.08 | 7.97 | -58.15 | 1 | 6 | -1 | 77 | 350.345 | 3 | ↓ |
| Mid Mid (pH 6-8) | -2.66 | 7.06 | -75.32 | 3 | 6 | 1 | 85 | 352.361 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Molecular_Solubility | 3.08 | Bitter DB |
| ALOGPS_SOLUBILITY | 1.06e-01 g/l | DrugBank-approved |
| Purity | 95% | Fluorochem |
| Purity | 95+% | Matrix Scientific |
| therap | antibacterial | MicroSource Spectrum |
| Indications | Antibiotic | KeyOrganics Bioactives |
| Target | Antifection | Selleck Chemicals |
| Therapy | antimicrobial | SMDC MicroSource |
| Warnings | IRRITANT | Matrix Scientific |
| Target | Others | Selleck Chemicals |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50380-1-O | Mycobacterium Smegmatis (cluster #1 Of 4), Other | Other | 4880 | 0.30 | Functional ≤ 10μM |
| Z50425-3-O | Plasmodium Falciparum (cluster #3 Of 22), Other | Other | 6310 | 0.29 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z50380 | Z50380 | Mycobacterium Smegmatis | 1440 | 0.33 | Functional ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 10000 | 0.28 | Functional ≤ 10μM |
No pre-computed analogs available. Try a structural similarity search.