| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 20th, 2005 | 27 | Yes |
Popular Name: 2-[4-chloro-3-[(4-methoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol 2-[4-chloro-3-[(4-methoxyphenyl)…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.22 | -8.98 | -10.88 | 4 | 6 | 0 | 99 | 394.851 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A1-1-E | Sodium/glucose Cotransporter 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 240 | 0.34 | Binding ≤ 10μM |
| SC5A2-1-E | Sodium/glucose Cotransporter 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.47 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SC5A1_HUMAN | P13866 | Sodium/glucose Cotransporter 1, Human | 240 | 0.34 | Binding ≤ 1μM |
| SC5A2_HUMAN | P31639 | Sodium/glucose Cotransporter 2, Human | 1 | 0.47 | Binding ≤ 1μM |
| SC5A1_HUMAN | P13866 | Sodium/glucose Cotransporter 1, Human | 240 | 0.34 | Binding ≤ 10μM |
| SC5A2_HUMAN | P31639 | Sodium/glucose Cotransporter 2, Human | 1 | 0.47 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Hexose transport | |
| Inositol transporters | |
| Na+-dependent glucose transporters |
