| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 24th, 2005 | 30 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 7.35 | 0.11 | -48.73 | 0 | 3 | -1 | 49 | 567.706 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PPARD-2-E | Peroxisome Proliferator-activated Receptor Delta (cluster #2 Of 2), Eukaryotic | Eukaryotes | 53 | 0.34 | Binding ≤ 10μM |
| PPARD-1-E | Peroxisome Proliferator-activated Receptor Delta (cluster #1 Of 2), Eukaryotic | Eukaryotes | 300 | 0.30 | Functional ≤ 10μM |
| Z81135-4-O | L6 (Skeletal Muscle Myoblast Cells) (cluster #4 Of 4), Other | Other | 30 | 0.35 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PPARD_HUMAN | Q03181 | Peroxisome Proliferator-activated Receptor Delta, Human | 53 | 0.34 | Binding ≤ 1μM |
| PPARD_HUMAN | Q03181 | Peroxisome Proliferator-activated Receptor Delta, Human | 53 | 0.34 | Binding ≤ 10μM |
| Z81135 | Z81135 | L6 (Skeletal Muscle Myoblast Cells) | 30 | 0.35 | Functional ≤ 10μM |
| PPARD_MOUSE | P35396 | Peroxisome Proliferator-activated Receptor Delta, Mouse | 300 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Import of palmitoyl-CoA into the mitochondrial matrix | |
| Nuclear Receptor transcription pathway | |
| Regulation of pyruvate dehydrogenase (PDH) complex |
