| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 28th, 2005 | 43 | No |
Popular Name: ethyl ethyl
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.30 | 10.52 | -48.64 | 5 | 10 | 1 | 148 | 614.833 | 12 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PLMN-2-E | Plasminogen (cluster #2 Of 2), Eukaryotic | Eukaryotes | 1200 | 0.19 | Binding ≤ 10μM |
| TRY2-1-E | Trypsin II (cluster #1 Of 3), Eukaryotic | Eukaryotes | 120 | 0.23 | Binding ≤ 10μM |
| UROK-2-E | Urokinase-type Plasminogen Activator (cluster #2 Of 4), Eukaryotic | Eukaryotes | 960 | 0.20 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| TRY2_BOVIN | Q29463 | Trypsin II, Bovin | 120 | 0.23 | Binding ≤ 1μM |
| UROK_HUMAN | P00749 | Urokinase-type Plasminogen Activator, Human | 960 | 0.20 | Binding ≤ 1μM |
| PLMN_HUMAN | P00747 | Plasminogen, Human | 1200 | 0.19 | Binding ≤ 10μM |
| TRY2_BOVIN | Q29463 | Trypsin II, Bovin | 120 | 0.23 | Binding ≤ 10μM |
| UROK_HUMAN | P00749 | Urokinase-type Plasminogen Activator, Human | 960 | 0.20 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases | |
| Degradation of the extracellular matrix | |
| Dissolution of Fibrin Clot | |
| Platelet degranulation | |
| Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-l | |
| Signaling by PDGF |
