| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 23rd, 2010 | 35 | Yes |
Popular Name: 2-[4-[[4,5-bis(4-methoxyphenyl)thiazol-2-yl]sulfanylmethyl]-2-methyl-phenoxy]acetic 2-[4-[[4,5-bis(4-methoxyphenyl)t…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.57 | 14.01 | -50.19 | 0 | 6 | -1 | 81 | 506.625 | 10 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PPARD-2-E | Peroxisome Proliferator-activated Receptor Delta (cluster #2 Of 2), Eukaryotic | Eukaryotes | 5670 | 0.21 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PPARD_HUMAN | Q03181 | Peroxisome Proliferator-activated Receptor Delta, Human | 5670 | 0.21 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Import of palmitoyl-CoA into the mitochondrial matrix | |
| Nuclear Receptor transcription pathway | |
| Regulation of pyruvate dehydrogenase (PDH) complex |
