| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 11th, 2010 | 37 | No |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.64 | 8.12 | -47.43 | 4 | 11 | -1 | 180 | 556.367 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| P2Y12-1-E | Purinergic Receptor P2Y12 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1900 | 0.22 | Binding ≤ 10μM |
| P2RX2-1-E | P2X Purinoceptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 117 | 0.26 | Functional ≤ 10μM |
| P2RY4-1-E | Pyrimidinergic Receptor P2Y4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10000 | 0.19 | Functional ≤ 10μM |
| P2RY6-1-E | Pyrimidinergic Receptor P2Y6 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 10000 | 0.19 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| P2Y12_HUMAN | Q9H244 | Purinergic Receptor P2Y12, Human | 1900 | 0.22 | Binding ≤ 10μM |
| P2RX2_RAT | P49653 | P2X Purinoceptor 2, Rat | 117 | 0.26 | Functional ≤ 10μM |
| P2RY4_HUMAN | P51582 | Pyrimidinergic Receptor P2Y4, Human | 10000 | 0.19 | Functional ≤ 10μM |
| P2RY6_HUMAN | Q15077 | Pyrimidinergic Receptor P2Y6, Human | 10000 | 0.19 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| ADP signalling through P2Y purinoceptor 12 | |
| G alpha (i) signalling events | |
| G alpha (q) signalling events | |
| P2Y receptors |
