| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 24th, 2006 | 20 | No |
Popular Name: 2-(4-chlorophenyl)imino-5-(2-thienylmethylene)thiazolidin-4-one 2-(4-chlorophenyl)imino-5-(2-thi…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.22 | 8.01 | -6.55 | 1 | 3 | 0 | 45 | 320.826 | 2 | ↓ |
| Ref Reference (pH 7) | 4.73 | 7.47 | -37.49 | 0 | 3 | -1 | 44 | 319.818 | 3 | ↓ |
| Hi High (pH 8-9.5) | 5.68 | 6.2 | -42.39 | 0 | 3 | -1 | 48 | 319.818 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MPIP2-1-E | Dual Specificity Phosphatase Cdc25B (cluster #1 Of 2), Eukaryotic | Eukaryotes | 4400 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MPIP2_HUMAN | P30305 | Dual Specificity Phosphatase Cdc25B, Human | 4400 | 0.37 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Cyclin A/B1 associated events during G2/M transition | |
| Cyclin A:Cdk2-associated events at S phase entry | |
| Cyclin B2 mediated events |
