UCSF

Dual Specificity Phosphatase Cdc25B, Human (240 Compounds)

Swissprot:
MPIP2_HUMAN
Stitch:
MPIP2_HUMAN
UniProt:
P30305
ChEMBL:
CHEMBL4804
Reactome:
REACT_1857
REACT_9029
REACT_2101
PDB:
1CWR (DOCK)
1CWS (DOCK)
1CWT (DOCK)
1QB0 (DOCK)
1YM9 (DOCK)
1YMD (DOCK)
1YMK (DOCK)
1YML (DOCK)
1YS0 (DOCK)
2A2K (DOCK)
2IFD (DOCK)
2IFV (DOCK)
2UZQ (DOCK)
3FQT (DOCK)
3FQU (DOCK)
CDC25B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 240 48 6 2
Binding ≤ 1μM 53 8 2 1

Reactome Network (3)

Reactome ID Description Species
REACT_1857 Cyclin A/B1 associated events during G2/M transition Homo sapiens
REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Homo sapiens
REACT_2101 Cyclin B2 mediated events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
MPIP1_HUMAN P30304 CHEMBL3775 Dual Specificity Phosphatase Cdc25A, Human 89
MPIP3_HUMAN P30307 CHEMBL2378 Dual Specificity Phosphatase Cdc25C, Human 13

Cyclin A:Cdk2-associated events at S phase entry

Uniprot Swissprot Chembl Description Number Shared
MPIP1_HUMAN P30304 CHEMBL3775 Dual Specificity Phosphatase Cdc25A, Human 89

Cyclin B2 mediated events

Uniprot Swissprot Chembl Description Number Shared
MPIP1_HUMAN P30304 CHEMBL3775 Dual Specificity Phosphatase Cdc25A, Human 89
MPIP3_HUMAN P30307 CHEMBL2378 Dual Specificity Phosphatase Cdc25C, Human 13
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MPIP2_MOUSE P30306 CHEMBL2723 Dual Specificity Phosphatase Cdc25B, Mouse 19 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MPIP1_HUMAN P30304 CHEMBL3775 Dual Specificity Phosphatase Cdc25A, Human 164 27 4 1
MPIP3_HUMAN P30307 CHEMBL2378 Dual Specificity Phosphatase Cdc25C, Human 24 2 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
MPIP2-1-E Dual Specificity Phosphatase Cdc25B (cluster #1 Of 2), Eukaryotic 187 48 6 2
MPIP2-2-E Dual Specificity Phosphatase Cdc25B (cluster #2 Of 2), Eukaryotic 86 0 0 0
Uniprot Swissprot Chembl Description Number Shared
MPIP1_HUMAN P30304 CHEMBL3775 Dual Specificity Phosphatase Cdc25A, Human 89
PTN1_HUMAN P18031 CHEMBL335 Protein-tyrosine Phosphatase 1B, Human 44
PTN2_HUMAN P17706 CHEMBL3807 T-cell Protein-tyrosine Phosphatase, Human 23
MPIP3_HUMAN P30307 CHEMBL2378 Dual Specificity Phosphatase Cdc25C, Human 13
PTPRC_HUMAN P08575 CHEMBL3243 Leukocyte Common Antigen, Human 7
PTN6_HUMAN P29350 CHEMBL3166 Protein-tyrosine Phosphatase 1C, Human 5
DUS1_MOUSE P28563 CHEMBL5623 Dual Specificity Protein Phosphatase 1, Mouse 4
DUS3_HUMAN P51452 CHEMBL2635 Dual Specificity Protein Phosphatase 3, Human 4
PTPRF_HUMAN P10586 CHEMBL3521 Receptor-type Tyrosine-protein Phosphatase F (LAR), Human 4
DUS6_RAT Q64346 CHEMBL5511 Dual Specificity Protein Phosphatase 6, Rat 3
I23O1_HUMAN P14902 CHEMBL4685 Indoleamine 2,3-dioxygenase, Human 3
PP1G_HUMAN P36873 CHEMBL4438 Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit, Human 2
YOPH_YEREN P15273 CHEMBL4404 Tyrosine-protein Phosphatase YopH, Yeren 2
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1
PTN11_HUMAN Q06124 CHEMBL3864 Protein-tyrosine Phosphatase 2C, Human 1

Most Common Rings