UCSF

Dual Specificity Protein Phosphatase 3, Human (58 Compounds)

Swissprot:
DUS3_HUMAN
Stitch:
DUS3_HUMAN
UniProt:
P51452
ChEMBL:
CHEMBL2635
Reactome:
REACT_12436
PDB:
1J4X (DOCK)
1VHR (DOCK)
3F81 (DOCK)
DUSP3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 58 19 1 1
Binding ≤ 1μM 6 0 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_12436 ERKs are inactivated Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DUS1_HUMAN P28562 CHEMBL6026 Dual Specificity Protein Phosphatase 1, Human 5 0 0 0
DUS22_HUMAN Q9NRW4 CHEMBL3924 Dual Specificity Phosphatase 22, Human 24 4 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
DUS3-1-E Dual Specificity Protein Phosphatase 3 (cluster #1 Of 3), Eukaryotic 30 14 0 1
DUS3-2-E Dual Specificity Protein Phosphatase 3 (cluster #2 Of 3), Eukaryotic 13 2 0 0
DUS3-3-E Dual Specificity Protein Phosphatase 3 (cluster #3 Of 3), Eukaryotic 15 3 1 0
Uniprot Swissprot Chembl Description Number Shared
MPIP1_HUMAN P30304 CHEMBL3775 Dual Specificity Phosphatase Cdc25A, Human 15
PTN1_HUMAN P18031 CHEMBL335 Protein-tyrosine Phosphatase 1B, Human 14
PTN7_HUMAN P35236 CHEMBL2219 Protein-tyrosine Phosphatase LC-PTP, Human 13
PTPRC_HUMAN P08575 CHEMBL3243 Leukocyte Common Antigen, Human 6
DUS1_HUMAN P28562 CHEMBL6026 Dual Specificity Protein Phosphatase 1, Human 5
MPIP2_MOUSE P30306 CHEMBL2723 Dual Specificity Phosphatase Cdc25B, Mouse 5
MPIP2_HUMAN P30305 CHEMBL4804 Dual Specificity Phosphatase Cdc25B, Human 4
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
MPIP3_HUMAN P30307 CHEMBL2378 Dual Specificity Phosphatase Cdc25C, Human 1
PP1A_HUMAN P62136 CHEMBL2164 Serine/threonine Protein Phosphatase PP1-alpha Catalytic Subunit, Human 1
PP1G_HUMAN P36873 CHEMBL4438 Serine/threonine Protein Phosphatase PP1-gamma Catalytic Subunit, Human 1
PPAC_HUMAN P24666 CHEMBL4903 Low Molecular Weight Phosphotyrosine Protein Phosphatase, Human 1
PTN12_HUMAN Q05209 CHEMBL3236 Protein-tyrosine Phosphatase G1, Human 1
PTN2_HUMAN P17706 CHEMBL3807 T-cell Protein-tyrosine Phosphatase, Human 1
PTN6_HUMAN P29350 CHEMBL3166 Protein-tyrosine Phosphatase 1C, Human 1
PTPRB_HUMAN P23467 CHEMBL2706 Receptor-type Tyrosine-protein Phosphatase Beta, Human 1
PTPRF_HUMAN P10586 CHEMBL3521 Receptor-type Tyrosine-protein Phosphatase F (LAR), Human 1
Q9AQH7_STAAU Q9AQH7 CHEMBL5643 DnaC Helicase, Staau 1

Most Common Rings