UCSF

ZINC00523925

Substance Information

In ZINC since Heavy atoms Benign functionality
July 24th, 2004 22 No

CAS Numbers: 21187-98-4 , [21187-98-4]

Other Names:

1-(3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl)-3-(4-methylphenyl)sulfonylurea

1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea

1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea; 1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea; BRN 1657836; Benzenesulfonamide, N-(((hexahydrocyclopenta(c)pyrrol-2(1H)-yl)amino)carbonyl)-4-methyl-; C15H21N3O3S; Diaikron; Diami

1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea; 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea; Gliclazide; Glimicron

1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea;Gliclazida [INN-Spanish];Gliclazidum [INN-Latin];N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea

1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulphonylurea

1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea

21187-98-4

21187-98-4; D01599; Gliclazide (JP16/INN); Glimicron (TN)

21187-98-4; Gliclazide; Prestwick_869

3-{hexahydro-1H-cyclopenta[c]pyrrol-2-yl}-1-(4-methylbenzenesulfonyl)urea

AB00053165

AB1004595

AC-12045

AC1L1G0Q

AKOS003237903

Benzenesulfonamide, N-(((hexahydrocyclopenta(c)pyrrol-2(1H)-yl)amino)carbonyl)-4-methyl-

benzenesulfonamide, N-[[(hexahydrocyclopenta[c]pyrrol-2(1H)-yl)amino]carbonyl]-4-methyl-

Bio-0502

BPBio1_000699

BRD-A61154809-001-04-3

BRN 1657836

BSPBio_000635

BSPBio_003304

C15H21N3O3S

CHEBI:31654

CHEMBL427216

CID3475

D01599

DAP000522

DB01120

DCF

Diabrezide

Diaikron

Diamicron

Diamicron MR

DivK1c_006966

EINECS 244-260-5

G2167_SIGMA

gli-

Gliclazida

Gliclazida [INN-Spanish]

Gliclazide (BAN

Gliclazide (Diamicron)

Gliclazide (JAN/INN)

Gliclazide [BAN:INN:DCF:JAN]

Gliclazidum

Gliclazidum [INN-Latin]

Gliklazid

Glimicron

Glimicron (TN)

Glyclazide

HMS1569P17

HMS1922D15

HMS2090K16

I06-0117

INN

INN)

JAN

KBio1_001910

KBio2_001958

KBio2_004526

KBio2_007094

KBio3_002806

KBioGR_001096

KBioSS_001958

LS-160299

MFCD00409893

MI

MI)

MLS001215197

MLS001304077

MLS001304118

MolPort-002-507-779

Mylan-Gliclazide

N-(4-Methylbenzenesulfonyl)-N'-(3-azabicyclo(3.3.0)oct-3-yl)urea

N-(hexahydrocyclopenta[c]pyrrol-2(1H)-ylcarbamoyl)-4-methylbenzenesulfonamide

N-[(hexahydrocyclopenta[c]pyrrol-2(1H)-ylamino)carbonyl]-4-methylbenzenesulfonamide

N/A

NCGC00095107-01

NCGC00095107-02

NCGC00095107-03

NCGC00095107-04

NCGC00095107-05

NCGC00095107-06

Nordialex

OR-1175

PMS-Gliclazide

Prestwick0_000558

Prestwick1_000558

Prestwick2_000558

Prestwick3_000558

Prestwick_869

S 1702

S 852

S-1702

S-852

SE 1702

SE-1702

SMR000542971

SPBio_002556

SpecPlus_000870

SPECTRUM1504145

SPECTRUM1505013

Spectrum3_001862

Spectrum4_000598

Spectrum5_000753

Spectrum_001478

STK803142

Unava

Urea, 1-(hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)-

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.25 2.44 -56.06 1 6 -1 85 322.41 4
Lo Low (pH 4.5-6) 1.45 4.69 -10.71 2 6 0 79 323.418 3

Vendor Notes

Note Type Comments Provided By
ALOGPS_SOLUBILITY 1.90e-01 g/l DrugBank-approved
biological_use Antidiabetic IBScreen Bioactives
therap antidiabetic, adhesion inhibitor MicroSource World Drugs
biological_use Antidiabetic IBScreen Bioactives
mechanism Appears to enhance glucose stimulated insulin secretion at a submaximally stimulating blood-glucose level IBScreen Bioactives
Patent Database Links EP1258253; EP1452526; EP1452530; EP1479666; EP1500403; EP1514550; EP1520582; EP1533292; EP1553091; EP1559710; EP1595544; EP1669345; EP1671637; EP1700848; EP1741435; EP1743655; EP1745775; EP1785144; EP1813273; EP1829858; EP1832576; EP1840134; EP1862450; EP ChEBI
biological_use Oral antihyperglycaemic agent IBScreen Bioactives
Target Others Selleck Chemicals
Target Potassium Channel Selleck Chemicals

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