| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 17th, 2010 | 8 | Yes |
Popular Name: DL-2,4-DIAMINOBUTYRIC ACID DIHYDROCHLORIDE DL-2,4-DIAMINOBUTYRIC ACID DIHYD…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 127531-11-7 , 1758-80-1 , 1883-09-6 , 19391-83-4 , 26908-94-1 , 305-62-4 , 65427-54-5 , 6970-28-1 , 73143-97-2 , [127531-11-7] , [26908-94-1] , [305-62-4] , [65427-54-5]
"DL-2,4-Diaminobutyric acid dihydrochloride, 98%"
(R)-2,4-Diaminobutanoic acid dihydrochloride
(R)-2,4-Diaminobutanoicaciddihydrochloride
(R)-2,4-Diaminobutyric acid dihydrochloride
(S)-2,4-Diaminobutanoicacidhydrobromide
2,4-Diamino-butyric acid dihydrochloride
2,4-Diamino-butyric acid(GABA)
2,4-Diaminobutanoic acid dihydrochloride
2,4-Diaminobutanoic acid hydrochloride
2,4-diaminobutanoic acid; 6970-28-1; nsc41117
2,4-diaminobutanoic acid; Dbu; alpha,gamma-diaminobutanoic acid; alpha,gamma-diaminobutyric acid
butanoic acid, 2,4-diamino-, dihydrochloride
D-2,4-Diaminobutyric acid DiHCl
D-2,4-Diaminobutyric acid dihydrochloride
D-Dab?ยค2HCl;D-2,4-Diaminobutyric acid dihydrochloride
Dl-2,4-diaminobutyric acid diHCl
DL-2,4-Diaminobutyric acid dihydrochloride, 99%
L-2,4-Diaminobutyric acid dihydrochloride
L-2,4-Diaminobutyricaciddihydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -3.96 | -1.92 | -65 | 5 | 4 | 0 | 94 | 118.136 | 3 | ↓ |
| Hi High (pH 8-9.5) | 4.34 | 8.66 | -10.34 | 3 | 5 | 0 | 76 | 445.357 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 194-196 °C | Indofine |
| MP | 203 | TCI |
| Purity | 95% | Fluorochem |
| Purity | 98% | Fluorochem |
| Purity | 99% min | APIChem |
| Melting_Point | ca 198? dec. | Alfa-Aesar |
| Melting_Point | ca 198° dec. | Alfa-Aesar |
| UniProt Database Links | NSPC_VIBAL | ChEBI |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| S6A11-1-E | GABA Transporter 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2000 | 1.00 | Binding ≤ 10μM |
| S6A12-1-E | Betaine Transporter (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2000 | 1.00 | Binding ≤ 10μM |
| S6A13-1-E | GABA Transporter 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 2000 | 1.00 | Binding ≤ 10μM |
| SC6A1-2-E | GABA Transporter 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 2000 | 1.00 | Binding ≤ 10μM |
| Z104301-2-O | GABA-A Receptor; Anion Channel (cluster #2 Of 8), Other | Other | 33 | 1.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104301 | Z104301 | GABA-A Receptor; Anion Channel | 33 | 1.31 | Binding ≤ 1μM |
| S6A12_RAT | P48056 | Betaine Transporter, Rat | 2000 | 1.00 | Binding ≤ 10μM |
| SC6A1_RAT | P23978 | GABA Transporter 1, Rat | 2000 | 1.00 | Binding ≤ 10μM |
| S6A13_RAT | P31646 | GABA Transporter 2, Rat | 2000 | 1.00 | Binding ≤ 10μM |
| S6A11_RAT | P31647 | GABA Transporter 3, Rat | 2000 | 1.00 | Binding ≤ 10μM |
| Z104301 | Z104301 | GABA-A Receptor; Anion Channel | 33 | 1.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Amino acid transport across the plasma membrane | |
| Na+/Cl- dependent neurotransmitter transporters | |
| Reuptake of GABA |
