In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
January 27th, 2011 | 27 | Yes |
Popular Name: 2-[4-(2,2-difluoroethyl)piperazin-1-yl]-N-[4-(2,4-dimethylphenyl)thiazol-2-yl]acetamide 2-[4-(2,2-difluoroethyl)piperazi…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.53 | 6.74 | -12.75 | 1 | 5 | 0 | 48 | 394.491 | 6 | ↓ |
Lo Low (pH 4.5-6) | 3.53 | 8.85 | -42.65 | 2 | 5 | 1 | 50 | 395.499 | 6 | ↓ |
No pre-computed analogs available. Try a structural similarity search.