UCSF

ZINC00607790

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
July 24th, 2004 29 Yes

Popular Name: Colchicine Colchicine

Find On: PubMed — Wikipedia — Google

CAS Numbers: 54192-66-4 , 64-86-8 , [64-86-8]

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.10 7.81 -20.49 1 7 0 83 399.443 5 ↓

Vendor Notes

Note Type Comments Provided By
MP 150-160 °C (dec.)(lit.) Indofine
MP 155 - 157 Enamine Building Blocks
MP 155...157 Enamine Building Blocks
ALOGPS_SOLUBILITY 2.76e-02 g/l DrugBank-approved
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Patent Database Links EP0970694; EP0984012; EP1104760; EP1229034; EP1438962; EP1516597; EP1574499; EP1669091; EP1698635; EP1757250; EP1780268; EP1808172; EP1813623; EP1870105; EP1889847; EP1947113; EP1967189; EP1982720; US2002037918; US2004097503; US2004132722; US2004171637; U ChEBI
UniProt Database Links GENL2_ORYSJ; MEFV_HUMAN ChEBI
Notes Plant tissue culture tested Apollo Scientific Bioactives
Reactome Database Links REACT_15538; REACT_163726; REACT_22239; REACT_22289 ChEBI

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Class C/3 (Metabotropic glutamate/pheromone receptors)
G alpha (i) signalling events

Analogs ( Draw Identity 99% 90% 80% 70% )