| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Functional ≤ 10μM | 1 | 1 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_257747 | Enzymatic degradation of dopamine by COMT | Mus musculus |
| REACT_234896 | Enzymatic degradation of Dopamine by monoamine oxidase | Mus musculus |
| REACT_231054 | Metabolism of serotonin | Mus musculus |
| REACT_230130 | Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2 | Mus musculus |
| REACT_242222 | Norepinephrine Neurotransmitter Release Cycle | Mus musculus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| AOFA_BOVIN | P21398 | CHEMBL3254 | Monoamine Oxidase A, Bovin | 173 | 66 | 8 | 5 |
| AOFA_HUMAN | P21397 | CHEMBL1951 | Monoamine Oxidase A, Human | 437 | 102 | 46 | 17 |
| AOFA_RAT | P21396 | CHEMBL3358 | Monoamine Oxidase A, Rat | 619 | 148 | 24 | 19 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| AOFA-1-E | Monoamine Oxidase A (cluster #1 Of 8), Eukaryotic | 225 | 93 | 17 | 15 |
| AOFA-2-E | Monoamine Oxidase A (cluster #2 Of 8), Eukaryotic | 578 | 109 | 8 | 2 |
| AOFA-3-E | Monoamine Oxidase A (cluster #3 Of 8), Eukaryotic | 33 | 13 | 2 | 2 |
| AOFA-4-E | Monoamine Oxidase A (cluster #4 Of 8), Eukaryotic | 202 | 58 | 35 | 7 |
| AOFA-5-E | Monoamine Oxidase A (cluster #5 Of 8), Eukaryotic | 22 | 6 | 1 | 1 |
| AOFA-6-E | Monoamine Oxidase A (cluster #6 Of 8), Eukaryotic | 123 | 15 | 1 | 0 |
| AOFA-7-E | Monoamine Oxidase A (cluster #7 Of 8), Eukaryotic | 1 | 1 | 1 | 0 |
| AOFA-8-E | Monoamine Oxidase A (cluster #8 Of 8), Eukaryotic | 21 | 4 | 2 | 2 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| GRM1_HUMAN | Q13255 | CHEMBL3772 | Metabotropic Glutamate Receptor 1, Human | 1 |
| GRM5_HUMAN | P41594 | CHEMBL3227 | Metabotropic Glutamate Receptor 5, Human | 1 |
| GRM5_RAT | P31424 | CHEMBL2564 | Metabotropic Glutamate Receptor 5, Rat | 1 |