UCSF

Caspase-1, Mouse (45 Compounds)

Swissprot:
CASP1_MOUSE
Stitch:
CASP1_MOUSE
UniProt:
P29452
ChEMBL:
CHEMBL4800
Reactome:
REACT_198700
REACT_198662
PDB:
Casp1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 45 1 0 0
Binding ≤ 1μM 37 1 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_198700 Interleukin-1 processing Mus musculus
REACT_198662 The AIM2 inflammasome Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CASP1_HUMAN P29466 CHEMBL4801 Caspase-1, Human 975 16 2 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CASP4_MOUSE P70343 CHEMBL1075276 Caspase-4, Mouse 0 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
CASP1-1-E Caspase-1 (cluster #1 Of 3), Eukaryotic 985 9 1 1
CASP1-2-E Caspase-1 (cluster #2 Of 3), Eukaryotic 29 7 0 0
CASP1-3-E Caspase-1 (cluster #3 Of 3), Eukaryotic 1 1 1 0
Uniprot Swissprot Chembl Description Number Shared
CASP3_HUMAN P42574 CHEMBL2334 Caspase-3, Human 20
CASP1_HUMAN P29466 CHEMBL4801 Caspase-1, Human 11
CASP8_HUMAN Q14790 CHEMBL3776 Caspase-8, Human 7
CASP9_HUMAN P55211 CHEMBL2273 Caspase-9, Human 7
CASP6_HUMAN P55212 CHEMBL3308 Caspase-6, Human 5
CASP7_HUMAN P55210 CHEMBL3468 Caspase-7, Human 4
CAN1_HUMAN P07384 CHEMBL3891 Calpain 1, Human 2
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 2
CATB_RAT P00787 CHEMBL2602 Cathepsin B, Rat 2