| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 28 | 0 | 0 | 1 |
| Binding ≤ 1μM | 20 | 0 | 0 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_198590 | Activation of Matrix Metalloproteinases | Rattus norvegicus |
| REACT_199177 | Collagen degradation | Rattus norvegicus |
| REACT_199178 | Degradation of the extracellular matrix | Rattus norvegicus |
| REACT_198631 | Trafficking and processing of endosomal TLR | Rattus norvegicus |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| CATK_HUMAN | P43235 | CHEMBL268 | Cathepsin K, Human | 1,590 | 27 | 10 | 16 |
| CATK_MOUSE | P55097 | CHEMBL1075277 | Cathepsin K, Mouse | 9 | 0 | 0 | 1 |
| CATK_RABIT | P43236 | CHEMBL3349 | Cathepsin K, Rabit | 94 | 2 | 2 | 3 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| CATK-1-E | Cathepsin K (cluster #1 Of 3), Eukaryotic | 1,509 | 16 | 10 | 14 |
| CATK-2-E | Cathepsin K (cluster #2 Of 3), Eukaryotic | 111 | 11 | 0 | 2 |
| CATK-3-E | Cathepsin K (cluster #3 Of 3), Eukaryotic | 20 | 1 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| CATK_HUMAN | P43235 | CHEMBL268 | Cathepsin K, Human | 28 |
| CATB_HUMAN | P07858 | CHEMBL4072 | Cathepsin B, Human | 4 |
| CATL1_HUMAN | P07711 | CHEMBL3837 | Cathepsin L, Human | 4 |
| CATS_HUMAN | P25774 | CHEMBL2954 | Cathepsin S, Human | 3 |
| CATH_HUMAN | P09668 | CHEMBL2225 | Cathepsin H, Human | 1 |