UCSF

Cytochrome P450 4A11, Human (35 Compounds)

Swissprot:
CP4AB_HUMAN
Stitch:
CP4AB_HUMAN
UniProt:
Q02928
ChEMBL:
CHEMBL3978
Reactome:
REACT_13645
REACT_13814
REACT_13425
REACT_116145
REACT_150134
REACT_150420
PDB:
CYP4A11

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 35 2 0 0
Binding ≤ 1μM 30 2 0 0

Reactome Network (6)

Reactome ID Description Species
REACT_13645 Eicosanoids Homo sapiens
REACT_13814 Fatty acids Homo sapiens
REACT_13425 Miscellaneous substrates Homo sapiens
REACT_116145 PPARA activates gene expression Homo sapiens
REACT_150134 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) Homo sapiens
REACT_150420 Synthesis of Leukotrienes (LT) and Eoxins (EX) Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
CP4F2_HUMAN P78329 CHEMBL3379 Cytochrome P450 4F2, Human 35

Fatty acids

Uniprot Swissprot Chembl Description Number Shared
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6, Human 18
CP4F2_HUMAN P78329 CHEMBL3379 Cytochrome P450 4F2, Human 35

Miscellaneous substrates

Uniprot Swissprot Chembl Description Number Shared
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6, Human 18
CP4F2_HUMAN P78329 CHEMBL3379 Cytochrome P450 4F2, Human 35

Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)

Uniprot Swissprot Chembl Description Number Shared
CP1A2_HUMAN P05177 CHEMBL3356 Cytochrome P450 1A2, Human 23
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9, Human 17
CP2CJ_HUMAN P33261 CHEMBL3622 Cytochrome P450 2C19, Human 11
CP4F2_HUMAN P78329 CHEMBL3379 Cytochrome P450 4F2, Human 35

Synthesis of Leukotrienes (LT) and Eoxins (EX)

Uniprot Swissprot Chembl Description Number Shared
CP4F2_HUMAN P78329 CHEMBL3379 Cytochrome P450 4F2, Human 35

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
CP4F2_HUMAN P78329 CHEMBL3379 Cytochrome P450 4F2, Human 35
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 14
CP4AA_RAT P08516 CHEMBL2681 Cytochrome P450 4A1, Rat 1
CP4AE_RAT P20817 CHEMBL2180 Cytochrome P450 4A3, Rat 1
PGH2_SHEEP P79208 CHEMBL4102 Cyclooxygenase-2, Sheep 1