ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (587)
Reactome (1)
Related By:
Pathway (0)
Organism (2)
Gene (1)
Org. Clust. (2)
ChEMBL (27)
Rings (14)

11-beta-hydroxysteroid Dehydrogenase 1, Mouse (587 Compounds)

Swissprot:: DHI1_MOUSE
Stitch:: DHI1_MOUSE
UniProt:: P50172
ChEMBL:: CHEMBL3910
Reactome:: REACT_207160
PDB:: 1Y5M (DOCK); 1Y5R (DOCK); 3GMD (DOCK); Hsd11b1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	587	47	3	8
Binding ≤ 1μM	524	32	2	7
Functional ≤ 10μM	2	2	2	0

Reactome ID	Description	Species
REACT_207160	Glucocorticoid biosynthesis	Mus musculus

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
DHI1_HUMAN	P28845	CHEMBL4235	11-beta-hydroxysteroid Dehydrogenase 1, Human	1,504	137	8	16
DHI1_RAT	P16232	CHEMBL2391	11-beta-hydroxysteroid Dehydrogenase 1, Rat	37	1	1	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
DHI2_MOUSE	P51661	CHEMBL3490	11-beta-hydroxysteroid Dehydrogenase 2, Mouse	21	1	1	1

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
DHI1-1-E	11-beta-hydroxysteroid Dehydrogenase 1 (cluster #1 Of 3), Eukaryotic	1,350	127	3	13
DHI1-2-E	11-beta-hydroxysteroid Dehydrogenase 1 (cluster #2 Of 3), Eukaryotic	36	7	5	3
DHI1-3-E	11-beta-hydroxysteroid Dehydrogenase 1 (cluster #3 Of 3), Eukaryotic	166	10	0	3

Uniprot	Swissprot	Chembl	Description	Number Shared
DHI1_HUMAN	P28845	CHEMBL4235	11-beta-hydroxysteroid Dehydrogenase 1, Human	564
DHI2_HUMAN	P80365	CHEMBL3746	11-beta-hydroxysteroid Dehydrogenase 2, Human	44
DHI2_MOUSE	P51661	CHEMBL3490	11-beta-hydroxysteroid Dehydrogenase 2, Mouse	21
DHI1_RAT	P16232	CHEMBL2391	11-beta-hydroxysteroid Dehydrogenase 1, Rat	8
NR1I2_HUMAN	O75469	CHEMBL3401	Pregnane X Receptor, Human	6
DHB1_HUMAN	P14061	CHEMBL3181	Estradiol 17-beta-dehydrogenase 1, Human	4
DHB2_HUMAN	P37059	CHEMBL2789	Estradiol 17-beta-dehydrogenase 2, Human	2
Q5XX84_CANFA	Q5XX84	CHEMBL5342	11-beta-hydroxysteroid Dehydrogenase Type 1, Canine	2
Z100494	Z100494	CHEMBL612655	C2C12 (Myoblast Cells)	2
Z80006	Z80006	CHEMBL614510	3T3-L1 (Fibroblast Cells)	2
3BHS2_HUMAN	P26439	CHEMBL3670	3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human	1
CAH12_HUMAN	O43570	CHEMBL3242	Carbonic Anhydrase XII, Human	1
CAH13_MOUSE	Q9D6N1	CHEMBL2186	Carbonic Anhydrase XIII, Mouse	1
CAH14_HUMAN	Q9ULX7	CHEMBL3510	Carbonic Anhydrase XIV, Human	1
CAH1_HUMAN	P00915	CHEMBL261	Carbonic Anhydrase I, Human	1
CAH2_HUMAN	P00918	CHEMBL205	Carbonic Anhydrase II, Human	1
CAH4_HUMAN	P22748	CHEMBL3729	Carbonic Anhydrase IV, Human	1
CAH5A_HUMAN	P35218	CHEMBL4789	Carbonic Anhydrase VA, Human	1
CAH5B_HUMAN	Q9Y2D0	CHEMBL3969	Carbonic Anhydrase VB, Human	1
CAH6_HUMAN	P23280	CHEMBL3025	Carbonic Anhydrase VI, Human	1
CAH7_HUMAN	P43166	CHEMBL2326	Carbonic Anhydrase VII, Human	1
CAH9_HUMAN	Q16790	CHEMBL3594	Carbonic Anhydrase IX, Human	1
DHI2_RAT	P50233	CHEMBL2908	11-beta-hydroxysteroid Dehydrogenase 2, Rat	1
KPCL_HUMAN	P24723	CHEMBL3616	Protein Kinase C Eta, Human	1
PTN11_HUMAN	Q06124	CHEMBL3864	Protein-tyrosine Phosphatase 2C, Human	1
Q56D22_MACMU	Q56D22	CHEMBL5227	Hydroxysteroid 11-beta Dehydrogenase 1, Macmu	1
SC5A7_RAT	Q9JMD7	CHEMBL5797	High Affinity Choline Transporter 1, Rat	1