| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 14 | 0 | 0 | 0 |
| Binding ≤ 1μM | 6 | 0 | 0 | 0 |
| Functional ≤ 10μM | 128 | 4 | 1 | 2 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_224460 | Apoptotic cleavage of cellular proteins | Mus musculus |
| REACT_188266 | Inactivation, recovery and regulation of the phototransduction cascade | Mus musculus |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FNTB_MOUSE | Q8K2I1 | CHEMBL2631 | Protein Farnesyltransferase Beta Subunit, Mouse | 130 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| FNTA_BOVIN | P29702 | CHEMBL2377 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin | 668 | 6 | 4 | 5 |
| FNTA_HUMAN | P49354 | CHEMBL271 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human | 1,900 | 11 | 6 | 5 |
| FNTA_RAT | Q04631 | CHEMBL4432 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat | 322 | 2 | 1 | 4 |
| FNTA_YEAST | P29703 | CHEMBL2406 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Yeast | 67 | 1 | 1 | 1 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| FNTA-1-E | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic | 2,644 | 14 | 6 | 7 |
| FNTA-1-F | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 2), Fungal | 51 | 0 | 0 | 0 |
| FNTA-2-E | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #2 Of 3), Eukaryotic | 54 | 2 | 2 | 0 |
| FNTA-2-F | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #2 Of 2), Fungal | 16 | 1 | 1 | 1 |
| FNTA-3-E | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #3 Of 3), Eukaryotic | 52 | 0 | 1 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FNTB_MOUSE | Q8K2I1 | CHEMBL2631 | Protein Farnesyltransferase Beta Subunit, Mouse | 130 |
| Z80951 | Z80951 | CHEMBL614822 | NIH3T3 (Fibroblasts) | 76 |
| PGTB1_MOUSE | Q8BUY9 | CHEMBL2295 | Geranylgeranyl Transferase Type I Beta Subunit, Mouse | 15 |
| FNTA_HUMAN | P49354 | CHEMBL271 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human | 12 |
| FNTB_HUMAN | P49356 | CHEMBL272 | Protein Farnesyltransferase Beta Subunit, Human | 12 |
| FNTA_BOVIN | P29702 | CHEMBL2377 | Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin | 1 |
| FNTB_BOVIN | P49355 | CHEMBL4671 | Protein Farnesyltransferase Beta Subunit, Bovin | 1 |
| PGTB1_BOVIN | Q5EAD5 | CHEMBL4347 | Geranylgeranyl Transferase Type I Beta Subunit, Bovin | 1 |
| RASH_HUMAN | P01112 | CHEMBL2167 | Transforming Protein P21/H-Ras-1, Human | 1 |
| Z50466 | Z50466 | CHEMBL368 | Trypanosoma Cruzi | 1 |
| Z80106 | Z80106 | CHEMBL614563 | COS-1 (Kidney Cells) | 1 |
| Z80211 | Z80211 | CHEMBL614721 | LoVo (Colon Adenocarcinoma Cells) | 1 |
| Z80224 | Z80224 | CHEMBL387 | MCF7 (Breast Carcinoma Cells) | 1 |
| Z80928 | Z80928 | CHEMBL394 | HCT-116 (Colon Carcinoma Cells) | 1 |
| Z81285 | Z81285 | CHEMBL615000 | NIH-H Cell Line | 1 |
| Z81286 | Z81286 | CHEMBL615001 | NIH-K Cell Line | 1 |