ZINC 12

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Swissprot:: FNTA_RAT
Stitch:: FNTA_RAT
UniProt:: Q04631
ChEMBL:: CHEMBL4432
PDB:: 1D8D (DOCK); 1D8E (DOCK); 1FPP (DOCK); 1FT1 (DOCK); 1FT2 (DOCK); 1FTI (DOCK); 1HZ7 (DOCK); 1JCR (DOCK); 1JCS (DOCK); 1KZO (DOCK); 1KZP (DOCK); 1KZR (DOCK); 1N4P (DOCK); 1N4Q (DOCK); 1N4R (DOCK); 1N4S (DOCK); 1N94 (DOCK); 1N95 (DOCK); 1N9A (DOCK); 1NI1 (DOCK); 1NL4 (DOCK); 1O1R (DOCK); 1O1S (DOCK); 1O1T (DOCK); 1O5M (DOCK); 1QBQ (DOCK); 1QE2 (DOCK); 1S64 (DOCK); 1SA5 (DOCK); 1TN7 (DOCK); 1TN8 (DOCK); 1TNB (DOCK); 1TNO (DOCK); 1TNU (DOCK); 1TNY (DOCK); 1TNZ (DOCK); 1X81 (DOCK); 2BED (DOCK); 2FTI (DOCK); 2R2L (DOCK); 2ZIR (DOCK); 2ZIS (DOCK); 3DPY (DOCK); 3E30 (DOCK); 3E32 (DOCK); 3E33 (DOCK); 3E34 (DOCK); 3EU5 (DOCK); 3EUV (DOCK); 3FTI (DOCK); 3KSL (DOCK); 3KSQ (DOCK); Fnta

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	322	2	1	4
Binding ≤ 1μM	297	2	1	4
Functional ≤ 10μM	28	0	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
FNTA_BOVIN	P29702	CHEMBL2377	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin	668	6	4	5
FNTA_HUMAN	P49354	CHEMBL271	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	1,900	11	6	5
FNTA_MOUSE	Q61239	CHEMBL2153	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Mouse	14	0	0	0
FNTA_YEAST	P29703	CHEMBL2406	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Yeast	67	1	1	1

Code	Description	Substances	Purchasable	Natural	In Man
FNTA-1-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 3), Eukaryotic	2,644	14	6	7
FNTA-1-F	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #1 Of 2), Fungal	51	0	0	0
FNTA-2-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #2 Of 3), Eukaryotic	54	2	2	0
FNTA-2-F	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #2 Of 2), Fungal	16	1	1	1
FNTA-3-E	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit (cluster #3 Of 3), Eukaryotic	52	0	1	0

Uniprot	Swissprot	Chembl	Description	Number Shared
FNTB_RAT	Q02293	CHEMBL4890	Protein Farnesyltransferase Beta Subunit, Rat	282
FNTA_HUMAN	P49354	CHEMBL271	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human	85
FNTB_HUMAN	P49356	CHEMBL272	Protein Farnesyltransferase Beta Subunit, Human	83
FNTA_BOVIN	P29702	CHEMBL2377	Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin	64
FNTB_BOVIN	P49355	CHEMBL4671	Protein Farnesyltransferase Beta Subunit, Bovin	64
Q5EI73_PLAFA	Q5EI73	CHEMBL4737	Protein Farnesyltransferase Alpha Subunit, Plafa	47
Q5EI74_PLAFA	Q5EI74	CHEMBL1741264	Protein Farnesyltransferase Beta Subunit, Plafa	47
PGTB1_HUMAN	P53609	CHEMBL4135	Geranylgeranyl Transferase Type I Beta Subunit, Human	44
PGTB1_BOVIN	Q5EAD5	CHEMBL4347	Geranylgeranyl Transferase Type I Beta Subunit, Bovin	31
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	22
RASH_HUMAN	P01112	CHEMBL2167	Transforming Protein P21/H-Ras-1, Human	7
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	4
Z80416	Z80416	CHEMBL614630	Rat1 (Fibroblast Cells)	3
FDFT_HUMAN	P37268	CHEMBL3338	Squalene Synthetase, Human	1
FDFT_RAT	Q02769	CHEMBL3815	Squalene Synthetase, Rat	1