UCSF

Squalene Synthetase, Rat (635 Compounds)

Swissprot:
FDFT_RAT
Stitch:
FDFT_RAT
UniProt:
Q02769
ChEMBL:
CHEMBL3815
Reactome:
REACT_198613
REACT_238041
REACT_196408
PDB:
Fdft1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 635 22 7 11
Binding ≤ 1μM 502 11 3 3

Reactome Network (3)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 299 5 1 5

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
FDFT-1-E Squalene Synthetase (cluster #1 Of 4), Eukaryotic 668 13 4 10
FDFT-2-E Squalene Synthetase (cluster #2 Of 4), Eukaryotic 26 1 1 2
FDFT-3-E Squalene Synthetase (cluster #3 Of 4), Eukaryotic 135 5 1 1
FDFT-4-E Squalene Synthetase (cluster #4 Of 4), Eukaryotic 56 8 2 2
Uniprot Swissprot Chembl Description Number Shared
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 60
FNTA_BOVIN P29702 CHEMBL2377 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin 12
FNTB_BOVIN P49355 CHEMBL4671 Protein Farnesyltransferase Beta Subunit, Bovin 12
CRTM_STAAU A9JQL9 CHEMBL5440 Dehydrosqualene Synthase, Staau 7
FNTA_HUMAN P49354 CHEMBL271 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human 4
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 4
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 2
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 2
ADRB2_BOVIN Q28044 CHEMBL3373 Beta-2 Adrenergic Receptor, Bovin 2
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 2
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 2
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 2
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 2
GGPPS_HUMAN O95749 CHEMBL4769 Geranylgeranyl Pyrophosphate Synthetase, Human 2
Q4CXF7_TRYCC Q4CXF7 CHEMBL5220 Farnesyltransferase, Putative, Trycc 2
Q4Q5W4_LEIMA Q4Q5W4 CHEMBL5223 Farnesyltransferase, Putative, Leima 2
FNTA_RAT Q04631 CHEMBL4432 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat 1
FNTA_YEAST P29703 CHEMBL2406 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Yeast 1
FNTB_RAT Q02293 CHEMBL4890 Protein Farnesyltransferase Beta Subunit, Rat 1
FNTB_YEAST P22007 CHEMBL4122 Protein Farnesyltransferase Beta Subunit, Yeast 1
FPPS_HUMAN P14324 CHEMBL1782 Farnesyl Diphosphate Synthase, Human 1