UCSF

Protein Farnesyltransferase Beta Subunit, Rat (258 Compounds)

Swissprot:
FNTB_RAT
Stitch:
FNTB_RAT
UniProt:
Q02293
ChEMBL:
CHEMBL4890
Reactome:
REACT_227662
PDB:
1D8D (DOCK)
1D8E (DOCK)
1FPP (DOCK)
1FT1 (DOCK)
1FT2 (DOCK)
1FTI (DOCK)
1HZ7 (DOCK)
1JCR (DOCK)
1JCS (DOCK)
1KZO (DOCK)
1KZP (DOCK)
1KZR (DOCK)
1N94 (DOCK)
1N95 (DOCK)
1N9A (DOCK)
1NI1 (DOCK)
1NL4 (DOCK)
1O1R (DOCK)
1O1S (DOCK)
1O1T (DOCK)
1O5M (DOCK)
1QBQ (DOCK)
1QE2 (DOCK)
1SA5 (DOCK)
1TN7 (DOCK)
1TN8 (DOCK)
1X81 (DOCK)
2BED (DOCK)
2FTI (DOCK)
2R2L (DOCK)
2ZIR (DOCK)
2ZIS (DOCK)
3DPY (DOCK)
3E30 (DOCK)
3E32 (DOCK)
3E33 (DOCK)
3E34 (DOCK)
3EU5 (DOCK)
3EUV (DOCK)
3FTI (DOCK)
3KSL (DOCK)
3KSQ (DOCK)
Fntb

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 258 1 0 2
Binding ≤ 1μM 233 1 0 2
Functional ≤ 10μM 28 0 0 0

Reactome Network (1)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
FNTB_BOVIN P49355 CHEMBL4671 Protein Farnesyltransferase Beta Subunit, Bovin 649 6 4 5
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 1,846 10 4 5
FNTB_MOUSE Q8K2I1 CHEMBL2631 Protein Farnesyltransferase Beta Subunit, Mouse 10 0 0 0
FNTB_YEAST P22007 CHEMBL4122 Protein Farnesyltransferase Beta Subunit, Yeast 62 1 1 1

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
FNTB-1-E Protein Farnesyltransferase Beta Subunit (cluster #1 Of 3), Eukaryotic 2,600 12 6 7
FNTB-1-F Protein Farnesyltransferase Beta Subunit (cluster #1 Of 2), Fungal 51 0 0 0
FNTB-2-E Protein Farnesyltransferase Beta Subunit (cluster #2 Of 3), Eukaryotic 42 2 0 0
FNTB-2-F Protein Farnesyltransferase Beta Subunit (cluster #2 Of 2), Fungal 11 1 1 1
FNTB-3-E Protein Farnesyltransferase Beta Subunit (cluster #3 Of 3), Eukaryotic 52 0 1 0
Uniprot Swissprot Chembl Description Number Shared
FNTA_RAT Q04631 CHEMBL4432 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Rat 282
FNTA_HUMAN P49354 CHEMBL271 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Human 77
FNTB_HUMAN P49356 CHEMBL272 Protein Farnesyltransferase Beta Subunit, Human 75
Q5EI73_PLAFA Q5EI73 CHEMBL4737 Protein Farnesyltransferase Alpha Subunit, Plafa 46
Q5EI74_PLAFA Q5EI74 CHEMBL1741264 Protein Farnesyltransferase Beta Subunit, Plafa 46
PGTB1_HUMAN P53609 CHEMBL4135 Geranylgeranyl Transferase Type I Beta Subunit, Human 41
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 22
RASH_HUMAN P01112 CHEMBL2167 Transforming Protein P21/H-Ras-1, Human 7
FNTA_BOVIN P29702 CHEMBL2377 Protein Farnesyltransferase/geranylgeranyltransferase Type I Alpha Subunit, Bovin 4
FNTB_BOVIN P49355 CHEMBL4671 Protein Farnesyltransferase Beta Subunit, Bovin 4
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 4
Z80416 Z80416 CHEMBL614630 Rat1 (Fibroblast Cells) 3
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 1
FDFT_RAT Q02769 CHEMBL3815 Squalene Synthetase, Rat 1