UCSF

Serine/threonine-protein Kinase MTOR, Mouse (58 Compounds)

Swissprot:
MTOR_MOUSE
Stitch:
MTOR_MOUSE
UniProt:
Q9JLN9
ChEMBL:
CHEMBL1255165
Reactome:
REACT_226151
REACT_196588
REACT_213550
REACT_255725
REACT_226341
REACT_241655
REACT_260675
REACT_261840

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 58 2 0 0
Binding ≤ 1μM 58 2 0 0

Reactome Network (8)

Reactome ID Description Species
REACT_226151 CD28 dependent PI3K/Akt signaling Mus musculus
REACT_196588 Constitutive PI3K/AKT Signaling in Cancer Mus musculus
REACT_213550 HSF1-dependent transactivation Mus musculus
REACT_255725 mTOR signalling Mus musculus
REACT_226341 PIP3 activates AKT signaling Mus musculus
REACT_241655 Release of eIF4E Mus musculus
REACT_260675 S6K1-mediated signalling Mus musculus
REACT_261840 VEGFR2 mediated vascular permeability Mus musculus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 912 27 2 6
MTOR_RAT P42346 CHEMBL1075134 Serine/threonine-protein Kinase MTOR, Rat 22 1 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
MTOR-1-E Serine/threonine-protein Kinase MTOR (cluster #1 Of 3), Eukaryotic 22 5 1 1
MTOR-2-E Serine/threonine-protein Kinase MTOR (cluster #2 Of 3), Eukaryotic 899 22 1 5
MTOR-3-E Serine/threonine-protein Kinase MTOR (cluster #3 Of 3), Eukaryotic 51 2 0 0
Uniprot Swissprot Chembl Description Number Shared
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 21
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 19
P3C2A_HUMAN O00443 CHEMBL1075102 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Subunit Alpha, Human 3
P3C2B_HUMAN O00750 CHEMBL5554 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Beta Polypeptide, Human 3
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 3
PI4KB_HUMAN Q9UBF8 CHEMBL3268 PI4-kinase Beta Subunit, Human 3
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 3
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 3
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 3
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 2
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 1

Most Common Rings