UCSF

Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Subunit Alpha, Human (3 Compounds)

Swissprot:
P3C2A_HUMAN
Stitch:
P3C2A_HUMAN
UniProt:
O00443
ChEMBL:
CHEMBL1075102
Reactome:
REACT_19400
REACT_120756
REACT_120836
REACT_120918
REACT_121025
PDB:
2AR5 (DOCK)
2IWL (DOCK)
2REA (DOCK)
2RED (DOCK)
PIK3C2A

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3 2 0 0
Binding ≤ 1μM 2 2 0 0

Reactome Network (5)

Reactome ID Description Species
REACT_19400 Golgi Associated Vesicle Biogenesis Homo sapiens
REACT_120756 Synthesis of PIPs at the early endosome membrane Homo sapiens
REACT_120836 Synthesis of PIPs at the Golgi membrane Homo sapiens
REACT_120918 Synthesis of PIPs at the late endosome membrane Homo sapiens
REACT_121025 Synthesis of PIPs at the plasma membrane Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 3

Synthesis of PIPs at the Golgi membrane

Uniprot Swissprot Chembl Description Number Shared
PI4KB_HUMAN Q9UBF8 CHEMBL3268 PI4-kinase Beta Subunit, Human 3
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 3

Synthesis of PIPs at the late endosome membrane

Uniprot Swissprot Chembl Description Number Shared
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 3

Synthesis of PIPs at the plasma membrane

Uniprot Swissprot Chembl Description Number Shared
P3C2B_HUMAN O00750 CHEMBL5554 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Beta Polypeptide, Human 3
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 3
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 3
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 3
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 3

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
MTOR_MOUSE Q9JLN9 CHEMBL1255165 Serine/threonine-protein Kinase MTOR, Mouse 3
P3C2B_HUMAN O00750 CHEMBL5554 Phosphatidylinositol-4-phosphate 3-kinase C2 Domain-containing Beta Polypeptide, Human 3
P85A_HUMAN P27986 CHEMBL2506 PI3-kinase P85-alpha Subunit, Human 3
PI4KB_HUMAN Q9UBF8 CHEMBL3268 PI4-kinase Beta Subunit, Human 3
PK3C3_HUMAN Q8NEB9 CHEMBL1075165 Phosphatidylinositol 3-kinase Catalytic Subunit Type 3, Human 3
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 3
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 3
PK3CG_HUMAN P48736 CHEMBL3267 PI3-kinase P110-gamma Subunit, Human 3
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 2
PRKDC_HUMAN P78527 CHEMBL3142 DNA-dependent Protein Kinase, Human 2
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 1

Most Common Rings