UCSF

Thioredoxin Reductase 2, Human (4 Compounds)

Swissprot:
TRXR2_HUMAN
Stitch:
TRXR2_HUMAN
UniProt:
Q9NNW7
ChEMBL:
CHEMBL2403
Reactome:
REACT_172715
PDB:
1W1E (DOCK)
TXNRD2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 4 1 0 0
Binding ≤ 1μM 1 0 0 0
Functional ≤ 10μM 7 0 1 0

Reactome Network (1)

Reactome ID Description Species
REACT_172715 Detoxification of Reactive Oxygen Species Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
TRXR1_HUMAN Q16881 CHEMBL1927 Thioredoxin Reductase 1, Human 10
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TRXR2_PLAF7 P61076 CHEMBL4547 Thioredoxin Reductase, Plaf7 7 6 1 0
TRXR2_RAT Q9Z0J5 CHEMBL5086 Thioredoxin Reductase 2, Mitochondrial, Rat 1 0 1 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TRXR1_HUMAN Q16881 CHEMBL1927 Thioredoxin Reductase 1, Human 5 1 0 0
TRXR3_HUMAN Q86VQ6 CHEMBL3793 Thioredoxin Reductase 3, Human 3 1 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
TRXR1_HUMAN Q16881 CHEMBL1927 Thioredoxin Reductase 1, Human 10
TRXR3_HUMAN Q86VQ6 CHEMBL3793 Thioredoxin Reductase 3, Human 9
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 7
Z81252 Z81252 CHEMBL400 MDA-MB-231 (Breast Adenocarcinoma Cells) 7
TRXR2_PLAF7 P61076 CHEMBL4547 Thioredoxin Reductase, Plaf7 2
GSHR_HUMAN P00390 CHEMBL2755 Glutathione Reductase, Human 1