ZINC 12

Navigation

• About

  • ZINC
  • BCIRC
  • Irwin Lab
  • Shoichet Lab
  • UCSF
  
  
  • Acknowledgements
  • Facts
  • Usage

• Search

  • By:
  • Text
  • Structure
  • Properties
  • Catalogs
  
  
  • ZINC
  • Targets
  • Rings
  • Combination

• Subsets

  • By:
  • Catalog
  • Property
  • Target
  • Ring
  • Cart

• Help

  • Introduction
  • FAQ
  • Scripting/API
  • Quick Search
  • Problems
  • Filtering
  • History

• Social

  • ZINC Fans
  • Decoy Club
  • DOCK Fans
  • Facebook
  • Twitter
  • Blog
  • Linkedin
• Quick Search

  ZINC ID or SMILES

• General
• Distributions & Clustering
• Downloads
• Targets
• Clustered Targets

PKChem

Binding 10μM Binding 1μM Functional 10μM ADME/T 10μM

Binding 1μM Targets with Highest Number of Available Compounds (9 in total)

Name (Uniprot)	Swissprot	ChEMBL	Description	Size	Browse	Download (Annotations)
GRM5_RAT	P31424	CHEMBL2564	Metabotropic glutamate receptor 5	3	Annotations Catalogs	SMILES SDF Mol2 Flexibase
GRM5_HUMAN	P41594	CHEMBL3227	Metabotropic glutamate receptor 5	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PPARG_MOUSE	P37238	CHEMBL2459	Peroxisome proliferator-activated receptor gamma	2	Annotations Catalogs	SMILES SDF Mol2 Flexibase
LUCI_PHOPE	Q27757	CHEMBL5150	Luciferin 4-monooxygenase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PK3CA_MOUSE	P42337	CHEMBL2499	PI3-kinase p110-alpha subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
PK3CD_HUMAN	O00329	CHEMBL3130	PI3-kinase p110-delta subunit	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
Q965D5_PLAFA	Q965D5	CHEMBL4150	Enoyl-acyl-carrier protein reductase	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
SHH_MOUSE	Q62226	CHEMBL5387	Sonic hedgehog protein	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase
TOP3_BACSU	P96583	CHEMBL4320	DNA topoisomerase III	1	Annotations Catalogs	SMILES SDF Mol2 Flexibase