| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 3rd, 2005 | 26 | Yes |
Popular Name: Vincamine Vincamine
Find On: PubMed — Wikipedia — Google
CAS Numbers: 10592-03-7 , 1617-90-9 , 1672-28-2 , 18374-18-0 , [1617-90-9]
10592-03-7; D08678; Vadicate (TN); Vincamine hydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.18 | 8.47 | -42.04 | 2 | 5 | 1 | 56 | 355.458 | 3 | ↓ |
| Hi High (pH 8-9.5) | 3.18 | 6.14 | -6.73 | 1 | 5 | 0 | 55 | 354.45 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 232 °C (dec.)(lit.) | Indofine |
| biological_source | Alkaloid from Tabernaemontana rigida (Apocynaceae) | ZereneX Building Blocks |
| PUBCHEM_PATENT_ID | EP0001021A2; EP0011057A1; EP0011059A1; EP0021923A1; EP0038619A2; EP0040507A1; EP0042818A1; EP0045918A1; EP0046506A1; EP0050492A1; EP0050589A1; EP0052085A2; EP0052238A1; EP0052917A2; EP0072932A2; EP0106443A2; EP0106443B1; EP0120832A1; EP0124067A1; EP012979 | IBM Patent Data |
| Patent Database Links | GB2078758; GB2214913; US2007010507 | ChEBI |
| biological_use | Hypotensive | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Potent blockers of voltage-gated Na[+] channels | IBScreen Bioactives |
| Indications | vasodilator | KeyOrganics Bioactives |
| biological_use | Vasodilator increasing blood flow to the brain | IBScreen Bioactives |
| MP | ~230o C | Indofine |
