| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 1st, 2008 | 16 | Yes |
Popular Name: AC1O52EX AC1O52EX
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.59 | 9.73 | -33.29 | 2 | 2 | 1 | 30 | 217.336 | 3 | ↓ |
| Mid Mid (pH 6-8) | 3.59 | 9.94 | -33.35 | 2 | 2 | 1 | 30 | 217.336 | 3 | ↓ |
| Mid Mid (pH 6-8) | 3.59 | 9.22 | -8.35 | 1 | 2 | 0 | 29 | 216.328 | 3 | ↓ |
| Mid Mid (pH 6-8) | 3.59 | 9.49 | -8.29 | 1 | 2 | 0 | 29 | 216.328 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH3-1-E | Histamine H3 Receptor (cluster #1 Of 3), Eukaryotic | Eukaryotes | 2 | 0.76 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH3_HUMAN | Q9Y5N1 | Histamine H3 Receptor, Human | 2.15 | 0.76 | Binding ≤ 1μM |
| HRH3_RAT | Q9QYN8 | Histamine H3 Receptor, Rat | 0.1 | 0.88 | Binding ≤ 1μM |
| HRH3_RAT | Q9QYN8 | Histamine H3 Receptor, Rat | 0.1 | 0.88 | Binding ≤ 10μM |
| HRH3_HUMAN | Q9Y5N1 | Histamine H3 Receptor, Human | 2.15 | 0.76 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Histamine receptors |
