UCSF

ZINC11820543

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
March 12th, 2008 28 Yes

Popular Name: (5R)-7-[(3,4-difluorophenyl)methyl]-3-[(6-methyl-2-pyridyl)methyl]-3,7-diazaspiro[4.5]decan-6-one (5R)-7-[(3,4-difluorophenyl)meth…

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Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 2.23 1.96 -41.21 1 4 1 38 386.466 4 ↓
Lo Low (pH 4.5-6) 2.23 1.99 -109.25 2 4 2 39 387.474 4 ↓

Activity (Go SEA)

Rings

Analogs ( Draw Identity 99% 90% 80% 70% )