UCSF

ZINC00121458

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since Heavy atoms Benign functionality
July 23rd, 2004 16 Yes

Popular Name: Sulfathiazole Sulfathiazole

Find On: PubMed — Wikipedia — Google

CAS Numbers: 144-74-1 , 169905-10-6 , 4151-50-2 , 72-14-0 , [144-74-1] , [4151-50-2] , [72-14-0]

Other Names:

2-(Sulfanilylamino)thiazole; 2-(p-Aminobenzenesulfonamido)thiazole; 2-(p-Aminobenzenesulphonamido)thiazole; 2-Sulfanilamidothiazol [German]; 2-Sulfanilamidothiazole; 2-Sulfonamidothiazole; 2090 R.P; 2090 RP; 4-Amino-N-2-thiazolylbenzenesulfonamide; AI3-01

2-(Sulfanilylamino)thiazole; 2-(p-Aminobenzenesulfonamido)thiazole; 2-(p-Aminobenzenesulphonamido)thiazole; 2-Sulfanilamidothiazol; 2-Sulfanilamidothiazole; 2-Sulfonamidothiazole; 4-Amino-N-2-thiazolylbenzenesulfonamide; N(1)-2-Thiazolylsulfanilamide; Sul

2-Sulfanilamidothiazole sodium salt; AI3-26815; Benzenesulfonamide, 4-amino-N-2-thiazolyl-, monosodium salt; EINECS 205-638-5; LS-147844; Monosodium 2-sulfanilamidothiazole; N(sup 1)-2-Thiazolylsulfanilamide sodium salt; Sodium 2-sulfanilamidothiazole; So

4-amino-N-(1,3-thiazol-2-yl)benzene-1-sulfonamide

4-amino-N-(1,3-thiazol-2-yl)benzenesulfonamide

4-Amino-N-(thiazol-2-yl)benzenesulfonamide

4-amino-N-1,3-thiazol-2-ylbenzenesulfonamide

4-Amino-N-thiazol-2-yl-benzenesulfonamide

72-14-0; C11169; Sulfathiazole

72-14-0; D01047; Sulfathiazole (USP/INN)

72-14-0; Prestwick_430; Sulfathiazole

Alstar

benzenesulfonamide, 4-amino-N-2-thiazolyl-

BRD-K14705039-001-05-7

CPD-11285; Neostrepsan; Norsulfasol; Norsulfazole; sulfathiazole

INN

MFCD00005319

MFCD00072133

MFCD02668766

N(1)-(2-Thiazolyl)sulfanilamide

N-Ethyl-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluoro-1-octanesulfonamide

N/A

Neo-Strepsan

NF)

Sodium sulfathiazole

Sodium sulfathiazole;Sulphathiazole

sodium [(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide

sulfa-

Sulfathiazole (BAN

Sulfathiazole (Triple Sulfa) (FDA); Sulfathiazole (BAN

Sulfathiazole sodium

Sulfathiazole sodium salt

Sulfathiazole, 99%

Sulfatiazol; sulfathiazol; sulfathiazole; sulfathiazolum

Sulfluramid

Sulfluramid, 99%+

Sulphathiazole

Sultrin

THIAZAMIDE

USP); Sulfathiazole (Triple Sulfa) (FDA); Sulfathiazole Sodium (MI

USP); Sulfathiazole Sodium (MI

[(4-aminophenyl)sulfonyl](1,3-thiazol-2-yl)azanide

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 1.76 1.09 -15.04 3 5 0 88 255.324 2 ↓
Mid Mid (pH 6-8) 0.83 0.53 -49.05 2 5 -1 87 254.316 3 ↓
Lo Low (pH 4.5-6) 1.76 0.95 -57.96 4 5 1 90 256.332 2 ↓

Vendor Notes

Note Type Comments Provided By
MP 200 TCI
Melting_Point 200-203? Alfa-Aesar
Melting_Point 200-203° Alfa-Aesar
MP 202 - 204 Enamine Building Blocks
MP 202...204 Enamine Building Blocks
ALOGPS_SOLUBILITY 9.21e-01 g/l DrugBank-approved
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 95% Fluorochem
Therapy antibacterial SMDC Iconix
Target Antifection Selleck Chemicals
mechanism Dihydrofolate reductase inhibitor IBScreen Bioactives IBScreen Bioactives
mechanism Dihydrofolate synthesis inhibitor IBScreen Bioactives
Patent Database Links EP1537858; EP1538164; EP1717247; US2003105066; US2007203079; US2007207222; US2007243132; WO2007103687 ChEBI
mechanism Folate-antagonist IBScreen Bioactives
Target Others Selleck Chemicals
biological_use Sulfonamide IBScreen Bioactives IBScreen Bioactives
biological_use Used in treatment of severe staphylococcal infections, but use restricted due to its systemic toxicity. IBScreen Bioactives

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Analogs ( Draw Identity 99% 90% 80% 70% )