UCSF

ZINC12354859

Substance Information

In ZINC since Heavy atoms Benign functionality
May 8th, 2008 25 Yes

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 3.24 -3.08 -41.71 6 5 1 101 332.383 4

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
UROK-1-E Urokinase-type Plasminogen Activator (cluster #1 Of 4), Eukaryotic Eukaryotes 8500 0.28 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
UROK_HUMAN P00749 Urokinase-type Plasminogen Activator, Human 8500 0.28 Binding ≤ 10μM

Reactome Annotations from Targets (via Uniprot)

Description Species
Dissolution of Fibrin Clot

Analogs ( Draw Identity 99% 90% 80% 70% )