UCSF

ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Synonyms (33)
Vendors (19)
Annotations (24)
Representations (1)
Notes (13)
Targets (0)
Clustered (0)
Reactome (0)
Rings (0)
Analogs (2)

ZINC12360704

12360704

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since	Heavy atoms	Benign functionality
May 9^th, 2008	22	No

Popular Name: CYCLIC AMP CYCLIC AMP

Find On: PubMed — Wikipedia — Google

CAS Numbers: 102029-77-6 , 37839-81-9 , 60-92-4 , 86594-35-6 , [37839-81-9] , [60-92-4]

Other Names:

"Adenosine-3',5'-cyclophosphate, 99%"

(4aR,6R,7R,7aS)-6-(6-Amino-9H-purin-9-yl)-2,7-dihydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine 2-oxide, sodium salt

3',5'-Amp sodium salt; Adenosine, cyclic 3',5'-(hydrogen phosphate)-, monosodium salt; Cyclic 3',5'-(hydrogen phosphate)adenosine monosodium salt; Cyclic 3',5'-amp sodium salt; Cyclic AMP sodium; LS-15117

3',5'-AMP; 3',5'-Cyclic AMP; Adenosine 3',5'-cyclic monophosphate; Adenosine 3',5'-cyclophosphate; Adenosine 3',5'-monophosphate; Adenosine 3',5'-phosphate; Adenosine 3',5'-phosphate monohydrate; Adenosine cyclic 3',5'-monophosphate; Adenosine cyclic 3',5

3',5'-cyclic AMP

3',5'-cyclic AMP(1-)

3',5'-cyclic AMP; 3',5'-cyclic AMP anion; adenosine 3',5'-cyclic monophosphate; adenosine 3',5'-cyclic monophosphate anion; adenosine 3',5'-cyclic monophosphate(1-)

3',5'-Cyclic AMP; 60-92-4; Adenosine 3',5'-cyclic phosphate; Adenosine 3',5'-phosphate; C00575; Cyclic AMP; Cyclic adenylic acid; cAMP

3',5'-cyclic AMP; 60-92-4; adenosine 3',5'-cyclic phosphate; adenosine cyclic-3',5'-monophosphate; adenosine cyclic-monophosphate; adenosine-3',5'-cyclic monophosphate; adenosine-3',5'-monophosphate; adenosine-cyclic-phosphate; adenosine-cyclic-phosphoric

3'5'-Cyclic AMP; 6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-D][1,3,2]dioxaphosphinine-2,7-diol 2-oxide; Acrasin; Adenosine 3',5'-cyclic monophosphate; Adenosine 3',5'-cyclic phosphate; Adenosine 3',5'-cyclophosphate; Adenosine 3',5'-monophosphate; Ad

3'5'-Cyclic AMP;6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-D][1,3,2]dioxaphosphinine-2,7-diol 2-oxide;Acrasin;Adenosine 3',5'-cyclic monophosphate;Adenosine 3',5'-cyclic phosphate;Adenosine 3',5'-cyclophosphate;Adenosine 3',5'-monophosphate;Adenosine

3,5-cyclic amp; 3'-5'-cyclic adenosine monophosphate; 3',5'-Cyclic AMP; 3'5'-cyclic AMP; 6-(6-Amino-9H-purin-9-yl)tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinine-2,7-diol 2-oxide; Acrasin; Adenosine 3,5'-cyclic monophosphorate; Adenosine 3,5'-cyclic mono

3_,5_-Cyclic AMP

adenosine 3',5'-cyclic monophosphate

Adenosine 3',5'-cyclic monophosphate sodium salt

Adenosine 3',5'-Cyclic Monophosphate Sodium Salt Hydrate

Adenosine 3',5'-cyclic monophosphate, 99+%

Adenosine 3_,5_-cyclophosphate

Adenosine cyclophosphate

Adenosine Cyclphosphate

Adenosine-3',5'-cyclic monophosphate

Adenosine-3',5'-cyclic monophosphate, 97%+

Adenosine-3',5'-cyclophosphate

Camp sodium salt

CHEBI:1325; CHEBI:41588; CHEBI:19827; CHEBI:11673

Cyclic amp tris salt

SMILES:

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-1.71	-0.05	-51.46	3	11	-1	158	328.201	1	↓ MOL2 SDF SMILES Flexibase

Vendor Notes

Note Type	Comments	Provided By
UniProt Database Links	18C_DROME; 3CP2_STRSQ; AAPK2_CAEEL; ABCA1_HUMAN; ABCA1_MOUSE; ABCCB_HUMAN; ACLP_MOUSE; ACSA_ECOLI; ACTHR_BOVIN; ACTHR_CAVPO; ACTHR_HUMAN; ACTHR_MESAU; ACTHR_MOUSE; ACTHR_PAPHA; ACTHR_PIG; ACTHR_SHEEP; ACTNB_DICDI; ADCY1_BOVIN; ADCY1_HUMAN; ADCY1_MOUSE; AD	ChEBI
Mp [°C]	260	Acros Organics
Purity	95%	Fluorochem
UniProt Database Links	ACLP_MOUSE; ADCY1_BOVIN; ADCY1_HUMAN; ADCY1_MOUSE; ADCY2_DROME; ADCY2_HUMAN; ADCY2_MOUSE; ADCY2_RAT; ADCY3_HUMAN; ADCY3_MOUSE; ADCY3_RAT; ADCY4_HUMAN; ADCY4_MOUSE; ADCY4_RAT; ADCY5_CANFA; ADCY5_HUMAN; ADCY5_MOUSE; ADCY5_RABIT; ADCY5_RAT; ADCY6_CANFA; ADCY	ChEBI
Hazard	C: Corrosive	Acros Organics
H phrase	H318: Causes serious eye damage	Acros Organics
H phrase	H318: Causes serious eye damage; H314: Causes severe skin burns and eye damage	Acros Organics
P phrase	P301 + P330 + P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting	Acros Organics
P phrase	P301 + P330 + P331: IF SWALLOWED: rinse mouth. Do NOT induce vomiting; P280: Wear eye protection/face protection; P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue r	Acros Organics
R phrase	R34: Causes burns.	Acros Organics
Reactome Database Links	REACT_1257; REACT_1292; REACT_1532; REACT_15399; REACT_18272; REACT_18315; REACT_18321; REACT_18397; REACT_19249; REACT_19387; REACT_1963; REACT_20564; REACT_23933; REACT_325; REACT_75751; REACT_75788; REACT_827	ChEBI
S phrase	S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.	Acros Organics
S phrase	S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39: Wear suitable protective clothing, gloves and eye/face protection.; S45: In case of accident or if you feel unwell, seek medical advice immediat	Acros Organics

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description	Species
Adenylate cyclase activating pathway	Gallus gallus Canis familiaris Caenorhabditis elegans Rattus norvegicus Mus musculus Danio rerio Xenopus tropicalis Taeniopygia guttata Sus scrofa Dictyostelium discoideum Homo sapiens Drosophila melanogaster Bos taurus
Cam-PDE 1 activation	Xenopus tropicalis Caenorhabditis elegans Gallus gallus Homo sapiens Bos taurus Canis familiaris Mus musculus Rattus norvegicus Danio rerio Taeniopygia guttata Drosophila melanogaster Sus scrofa
CREB phosphorylation through the activation of Adenylate Cyclase	Rattus norvegicus Xenopus tropicalis Sus scrofa Caenorhabditis elegans Homo sapiens Drosophila melanogaster Mus musculus Canis familiaris Bos taurus Dictyostelium discoideum Taeniopygia guttata Danio rerio Gallus gallus
DARPP-32 events	Danio rerio Canis familiaris Saccharomyces cerevisiae Bos taurus Caenorhabditis elegans Schizosaccharomyces pombe Sus scrofa Rattus norvegicus Xenopus tropicalis Mus musculus Dictyostelium discoideum Taeniopygia guttata Gallus gallus Drosophila melanogaster Homo sapiens
G alpha (i) signalling events	Mus musculus Sus scrofa Caenorhabditis elegans Canis familiaris Drosophila melanogaster Homo sapiens Dictyostelium discoideum Xenopus tropicalis Gallus gallus Bos taurus Taeniopygia guttata Danio rerio Rattus norvegicus
G alpha (s) signalling events	Xenopus tropicalis Drosophila melanogaster Dictyostelium discoideum Canis familiaris Mus musculus Sus scrofa Bos taurus Homo sapiens Danio rerio Rattus norvegicus Taeniopygia guttata Caenorhabditis elegans Gallus gallus
G alpha (z) signalling events	Xenopus tropicalis Danio rerio Rattus norvegicus Gallus gallus Bos taurus Caenorhabditis elegans Mus musculus Homo sapiens Dictyostelium discoideum Drosophila melanogaster Canis familiaris Sus scrofa Taeniopygia guttata
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Drosophila melanogaster Gallus gallus Rattus norvegicus Dictyostelium discoideum Taeniopygia guttata Sus scrofa Bos taurus Xenopus tropicalis Canis familiaris Mus musculus Homo sapiens Danio rerio Caenorhabditis elegans
Glycolysis	Sus scrofa Mus musculus Bos taurus Canis familiaris Rattus norvegicus Homo sapiens Schizosaccharomyces pombe Xenopus tropicalis Arabidopsis thaliana Dictyostelium discoideum Oryza sativa Taeniopygia guttata Saccharomyces cerevisiae Danio rerio Caenorhabditis elegans Plasmodium falciparum Gallus gallus Drosophila melanogaster
HCN channels	Homo sapiens Drosophila melanogaster Gallus gallus Xenopus tropicalis Sus scrofa Caenorhabditis elegans Mus musculus Canis familiaris Taeniopygia guttata Danio rerio Arabidopsis thaliana Oryza sativa Rattus norvegicus Bos taurus
PDE3B signalling	Dictyostelium discoideum Danio rerio Mus musculus Sus scrofa Caenorhabditis elegans Homo sapiens Taeniopygia guttata Gallus gallus Xenopus tropicalis Bos taurus Canis familiaris Rattus norvegicus
PKA activation	Dictyostelium discoideum Xenopus tropicalis Taeniopygia guttata Mus musculus Rattus norvegicus Schizosaccharomyces pombe Sus scrofa Danio rerio Bos taurus Homo sapiens Drosophila melanogaster Caenorhabditis elegans Canis familiaris Saccharomyces cerevisiae Gallus gallus
PKA activation in glucagon signalling	Sus scrofa Dictyostelium discoideum Canis familiaris Homo sapiens Schizosaccharomyces pombe Drosophila melanogaster Rattus norvegicus Taeniopygia guttata Xenopus tropicalis Mus musculus Danio rerio Gallus gallus Bos taurus Caenorhabditis elegans Saccharomyces cerevisiae
Rap1 signalling	Homo sapiens Canis familiaris Rattus norvegicus Sus scrofa Drosophila melanogaster Mus musculus Danio rerio Caenorhabditis elegans Xenopus tropicalis Taeniopygia guttata Bos taurus Gallus gallus
Regulation of insulin secretion	Taeniopygia guttata Canis familiaris Xenopus tropicalis Drosophila melanogaster Danio rerio Mus musculus Homo sapiens Sus scrofa Gallus gallus Bos taurus Rattus norvegicus
Uptake and function of anthrax toxins	Homo sapiens
Vasopressin regulates renal water homeostasis via Aquaporins	Drosophila melanogaster Bos taurus Danio rerio Schizosaccharomyces pombe Gallus gallus Saccharomyces cerevisiae Mus musculus Caenorhabditis elegans Dictyostelium discoideum Homo sapiens Sus scrofa Taeniopygia guttata Rattus norvegicus Canis familiaris Xenopus tropicalis

Analogs ( Draw Identity 99% 90% 80% 70% )

Synonyms (33)
Vendors (19)
Annotations (24)
Representations (1)
Notes (13)
Targets (0)
Clustered (0)
Reactome (0)
Rings (0)
Analogs (2)