| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| May 25th, 2008 | 23 | No |
Popular Name: (5Z)-5-[[4-(p-tolylmethoxy)phenyl]methylene]thiazolidine-2,4-dione (5Z)-5-[[4-(p-tolylmethoxy)pheny…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.58 | 6.96 | -8.79 | 1 | 4 | 0 | 59 | 325.389 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PGDH-1-E | 15-hydroxyprostaglandin Dehydrogenase [NAD+] (cluster #1 Of 1), Eukaryotic | Eukaryotes | 232 | 0.40 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PGDH_HUMAN | P15428 | 15-hydroxyprostaglandin Dehydrogenase [NAD+], Human | 232 | 0.40 | Binding ≤ 1μM |
| PGDH_HUMAN | P15428 | 15-hydroxyprostaglandin Dehydrogenase [NAD+], Human | 232 | 0.40 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Synthesis of Lipoxins (LX) | |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) |
