| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 29th, 2010 | 24 | No |
Popular Name: (5Z)-5-[[4-[(4-methoxyphenyl)methoxy]phenyl]methylene]thiazolidine-2,4-dione (5Z)-5-[[4-[(4-methoxyphenyl)met…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.19 | 5.58 | -10.15 | 1 | 5 | 0 | 68 | 341.388 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PGDH-1-E | 15-hydroxyprostaglandin Dehydrogenase [NAD+] (cluster #1 Of 1), Eukaryotic | Eukaryotes | 529 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PGDH_HUMAN | P15428 | 15-hydroxyprostaglandin Dehydrogenase [NAD+], Human | 529 | 0.37 | Binding ≤ 1μM |
| PGDH_HUMAN | P15428 | 15-hydroxyprostaglandin Dehydrogenase [NAD+], Human | 529 | 0.37 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Synthesis of Lipoxins (LX) | |
| Synthesis of Prostaglandins (PG) and Thromboxanes (TX) |
