| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 19th, 2008 | 19 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.40 | 7.5 | -29.81 | 5 | 5 | 1 | 86 | 277.735 | 5 | ↓ |
| Hi High (pH 8-9.5) | 2.40 | 7.52 | -10.02 | 4 | 5 | 0 | 84 | 276.727 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| UROK-4-E | Urokinase-type Plasminogen Activator (cluster #4 Of 4), Eukaryotic | Eukaryotes | 920 | 0.44 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| UROK_HUMAN | P00749 | Urokinase-type Plasminogen Activator, Human | 920 | 0.44 | Binding ≤ 1μM |
| UROK_HUMAN | P00749 | Urokinase-type Plasminogen Activator, Human | 920 | 0.44 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Dissolution of Fibrin Clot |
