| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 19th, 2008 | 22 | Yes |
Popular Name: [4-(4-fluorophenyl)-2,6-diisopropyl-5-methyl-3-pyridyl]methanol [4-(4-fluorophenyl)-2,6-diisopro…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.24 | 7.95 | -5.67 | 1 | 2 | 0 | 33 | 301.405 | 4 | ↓ |
| Lo Low (pH 4.5-6) | 5.24 | 8.28 | -25.74 | 2 | 2 | 1 | 34 | 302.413 | 4 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| PUBCHEM_PATENT_ID | EP0934274A1; WO1998004528A2 | IBM Patent Data |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLR-2-E | Glucagon Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 7500 | 0.33 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLR_HUMAN | P47871 | Glucagon Receptor, Human | 7500 | 0.33 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Glucagon signaling in metabolic regulation | |
| Glucagon-type ligand receptors |
