| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 19th, 2008 | 25 | Yes |
Popular Name: Methyl2,6-Diisopropyl-4-(4-fluorophenyl)-5-hydroxymethyl-pyridine-3-carboxylate Methyl2,6-Diisopropyl-4-(4-fluor…
Find On: PubMed — Wikipedia — Google
CAS Number: 202859-11-8
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.63 | 8.1 | -7.83 | 1 | 4 | 0 | 59 | 345.414 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLR-2-E | Glucagon Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 9500 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLR_HUMAN | P47871 | Glucagon Receptor, Human | 9500 | 0.28 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| G alpha (s) signalling events | |
| Glucagon signaling in metabolic regulation | |
| Glucagon-type ligand receptors |
