| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 19th, 2008 | 28 | No |
Popular Name: 2-[1-benzyl-2-ethyl-4-(2-hydrazino-2-oxo-ethoxy)indol-3-yl]acetamide 2-[1-benzyl-2-ethyl-4-(2-hydrazi…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.12 | 6.06 | -21.27 | 5 | 7 | 0 | 112 | 380.448 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PA2GA-1-E | Phospholipase A2, Membrane Associated (cluster #1 Of 3), Eukaryotic | Eukaryotes | 121 | 0.35 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PA2GA_HUMAN | P14555 | Phospholipase A2 Group IIA, Human | 121 | 0.35 | Binding ≤ 1μM |
| PA2GA_HUMAN | P14555 | Phospholipase A2 Group IIA, Human | 121 | 0.35 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Acyl chain remodelling of PC | |
| Acyl chain remodelling of PE | |
| Acyl chain remodelling of PG | |
| Acyl chain remodelling of PI | |
| Acyl chain remodelling of PS | |
| Synthesis of PA |
