In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 20th, 2008 | 27 | Yes |
Popular Name: (1R)-1-(3-chlorophenyl)-2-[[(1S)-2-(7-isopropoxy-1H-indol-3-yl)-1-methyl-ethyl]amino]ethanol (1R)-1-(3-chlorophenyl)-2-[[(1S)…
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.60 | 8.67 | -44.95 | 4 | 4 | 1 | 62 | 387.931 | 8 | ↓ |
Hi High (pH 8-9.5) | 4.60 | 7.48 | -6.59 | 3 | 4 | 0 | 57 | 386.923 | 8 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ADRB3-1-E | Beta-3 Adrenergic Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 3 | 0.44 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
ADRB3_HUMAN | P13945 | Beta-3 Adrenergic Receptor, Human | 2.8 | 0.44 | Functional ≤ 10μM |
Description | Species |
---|---|
Adrenoceptors | |
G alpha (s) signalling events |