| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 22 | No |
Popular Name: Cyclohexyl [1,1'-biphenyl]-3-ylcarbamate Cyclohexyl [1,1'-biphenyl]-3-ylc…
Find On: PubMed — Wikipedia — Google
CAS Numbers: 565460-15-3 , [565460-15-3]
'Cyclohexyl [1,1''-biphenyl]-3-ylcarbamate'
biphenyl-3-ylcarbamic acid cyclohexyl ester
cyclohexyl biphenyl-3-ylcarbamate
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.32 | 9.69 | -7.11 | 1 | 3 | 0 | 38 | 295.382 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FAAH1-1-E | Anandamide Amidohydrolase (cluster #1 Of 7), Eukaryotic | Eukaryotes | 5754 | 0.33 | Binding ≤ 10μM |
| MGLL-2-E | Monoglyceride Lipase (cluster #2 Of 7), Eukaryotic | Eukaryotes | 10000 | 0.32 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FAAH1_HUMAN | O00519 | Anandamide Amidohydrolase, Human | 5650 | 0.33 | Binding ≤ 10μM |
| MGLL_HUMAN | Q99685 | Monoglyceride Lipase, Human | 10000 | 0.32 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Acyl chain remodeling of DAG and TAG | |
| Arachidonate production from DAG | |
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
No pre-computed analogs available. Try a structural similarity search.