| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 89 | 48 | 14 | 2 |
| Binding ≤ 1μM | 27 | 10 | 2 | 1 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_121122 | Acyl chain remodeling of DAG and TAG | Homo sapiens |
| REACT_19308 | Arachidonate production from DAG | Homo sapiens |
| REACT_494 | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | Homo sapiens |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| MGLL_MOUSE | O35678 | CHEMBL5774 | Monoglyceride Lipase, Mouse | 50 | 7 | 1 | 1 |
| MGLL_RAT | Q8R431 | CHEMBL3321 | Monoglyceride Lipase, Rat | 9 | 4 | 0 | 0 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| MGLL-1-E | Monoglyceride Lipase (cluster #1 Of 7), Eukaryotic | 12 | 4 | 0 | 0 |
| MGLL-2-E | Monoglyceride Lipase (cluster #2 Of 7), Eukaryotic | 88 | 38 | 10 | 0 |
| MGLL-3-E | Monoglyceride Lipase (cluster #3 Of 7), Eukaryotic | 6 | 1 | 1 | 1 |
| MGLL-4-E | Monoglyceride Lipase (cluster #4 Of 7), Eukaryotic | 2 | 0 | 0 | 0 |
| MGLL-5-E | Monoglyceride Lipase (cluster #5 Of 7), Eukaryotic | 15 | 9 | 1 | 0 |
| MGLL-6-E | Monoglyceride Lipase (cluster #6 Of 7), Eukaryotic | 23 | 7 | 3 | 2 |
| MGLL-7-E | Monoglyceride Lipase (cluster #7 Of 7), Eukaryotic | 2 | 1 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| FAAH1_HUMAN | O00519 | CHEMBL2243 | Anandamide Amidohydrolase, Human | 16 |
| FAAH1_RAT | P97612 | CHEMBL3229 | Anandamide Amidohydrolase, Rat | 12 |
| FAAH1_MOUSE | O08914 | CHEMBL3455 | Anandamide Amidohydrolase, Mouse | 3 |
| PA24A_HUMAN | P47712 | CHEMBL3816 | Cytosolic Phospholipase A2, Human | 3 |
| CNR1_MOUSE | P47746 | CHEMBL3037 | Cannabinoid CB1 Receptor, Mouse | 2 |
| CNR1_RAT | P20272 | CHEMBL3571 | Cannabinoid CB1 Receptor, Rat | 2 |
| GSK3A_HUMAN | P49840 | CHEMBL2850 | Glycogen Synthase Kinase-3 Alpha, Human | 2 |
| GSK3B_HUMAN | P49841 | CHEMBL262 | Glycogen Synthase Kinase-3 Beta, Human | 2 |
| ABHD6_MOUSE | Q8R2Y0 | CHEMBL5010 | Monoacylglycerol Lipase ABHD6, Mouse | 1 |
| MGLL_MOUSE | O35678 | CHEMBL5774 | Monoglyceride Lipase, Mouse | 1 |
| MGLL_RAT | Q8R431 | CHEMBL3321 | Monoglyceride Lipase, Rat | 1 |
| PA24B_HUMAN | P0C869 | CHEMBL4136 | Phospholipase A2 Group 1VB, Human | 1 |
| PA24C_HUMAN | Q9UP65 | CHEMBL4834 | Cytosolic Phospholipase A2 Gamma, Human | 1 |