UCSF

Phospholipase A2 Group 1VB, Human (57 Compounds)

Swissprot:
PA24B_HUMAN
Stitch:
PA24B_HUMAN
UniProt:
P0C869
ChEMBL:
CHEMBL4136
Reactome:
REACT_120829
REACT_121369
REACT_121324
REACT_121384
REACT_120977
REACT_120906
REACT_18273
PDB:
PLA2G4B

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 57 1 1 0
Binding ≤ 1μM 39 1 1 0
Functional ≤ 10μM 2 0 0 0

Reactome Network (7)

Reactome ID Description Species
REACT_120829 Acyl chain remodelling of PC Homo sapiens
REACT_121369 Acyl chain remodelling of PE Homo sapiens
REACT_121324 Acyl chain remodelling of PG Homo sapiens
REACT_121384 Acyl chain remodelling of PS Homo sapiens
REACT_120977 Hydrolysis of LPC Homo sapiens
REACT_120906 Synthesis of PA Homo sapiens
REACT_18273 XBP1(S) activates chaperone genes Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 23
PA24C_HUMAN Q9UP65 CHEMBL4834 Cytosolic Phospholipase A2 Gamma, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22
PA2G6_HUMAN O60733 CHEMBL3213 Calcium-independent Phospholipase A2, Human 22

Acyl chain remodelling of PE

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 23
PA24C_HUMAN Q9UP65 CHEMBL4834 Cytosolic Phospholipase A2 Gamma, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22
PA2G6_HUMAN O60733 CHEMBL3213 Calcium-independent Phospholipase A2, Human 22

Acyl chain remodelling of PG

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22

Acyl chain remodelling of PS

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22

Hydrolysis of LPC

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 23
PA24C_HUMAN Q9UP65 CHEMBL4834 Cytosolic Phospholipase A2 Gamma, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22

Synthesis of PA

Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
PA24B-1-E Phospholipase A2 Group 1VB (cluster #1 Of 2), Eukaryotic 56 0 0 0
PA24B-2-E Phospholipase A2 Group 1VB (cluster #2 Of 2), Eukaryotic 1 1 1 0
Uniprot Swissprot Chembl Description Number Shared
PA24A_HUMAN P47712 CHEMBL3816 Cytosolic Phospholipase A2, Human 23
PA24C_HUMAN Q9UP65 CHEMBL4834 Cytosolic Phospholipase A2 Gamma, Human 23
PA24D_HUMAN Q86XP0 CHEMBL2287 Phospholipase A2 Group 1VD, Human 22
PA2G6_HUMAN O60733 CHEMBL3213 Calcium-independent Phospholipase A2, Human 22
FAAH1_RAT P97612 CHEMBL3229 Anandamide Amidohydrolase, Rat 2
FAAH1_HUMAN O00519 CHEMBL2243 Anandamide Amidohydrolase, Human 1
MGLL_HUMAN Q99685 CHEMBL4191 Monoglyceride Lipase, Human 1

Most Common Rings