| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 21st, 2008 | 24 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.71 | 8.15 | -44.33 | 2 | 5 | -1 | 81 | 357.695 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRIK1-2-E | Glutamate Receptor Ionotropic Kainate 1 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 5000 | 0.31 | Binding ≤ 10μM |
| GRIK1-1-E | Glutamate Receptor Ionotropic Kainate 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 5000 | 0.31 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRIK1_HUMAN | P39086 | Glutamate Receptor Ionotropic Kainate 1, Human | 5000 | 0.31 | Binding ≤ 10μM |
| GRIK1_HUMAN | P39086 | Glutamate Receptor Ionotropic Kainate 1, Human | 5000 | 0.31 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Ca-permeable Kainate Receptor | |
| Activation of Na-permeable Kainate Receptors |
